Standard farmaceutici

Applications 6,7-Dibromo-2-naphthalenecarbonitrile is an intermediate in the synthesis of potent and orally active small molecule PTP1B inhibitors.
References Han, Y.X., et al.: Bioorg. Med. Chem. Lett., 18, 3200 (2008);

Applications (2S,3S)-3-Hydroxy-2-methyl-butanoic Acid Methyl Ester is an intermediate in the synthesis of (+)-Echimidine N-Oxide, which is a a hepatotoxic pyrrolizidine alkaloid. Different extracts and echimidine-N-oxide from Symphytum sylvaticum Boiss. Subsp. sepulcrale, has been shown to have Antifungal activity.
References Kartal, M., et al.: Turkish, J. Med. Sci., 31, 487 (2001); Cao, Y., J. Food Comp. Anal., 29, 106 (2013);

Applications An intermediate for the synthesis of a benzimidazole PARP inhibitor I (succinate salt) (ABT-472).
References Denny, W., et al.: J. Med. Chem., 33, 814 (1990), Anon., et al.: Curr. Med. Chem., 10, 321 (2003),

Applications 9-O-Methyl-3-O-pivaloyl-isourolithin A is a proposed intermediate in the synthesis of Isourolithin A 9-Glucuronide (I917525), which is a metabolite of ellagitannins and ellagic acid in different mammals.
References Gonzalez-Barrio, R., et al.: J. Agric. Food Chem., 59, 1152 (2011)

Applications 2-Acetamido-3-(benzyloxy)benzoic Acid Methyl Ester is an intermediate in the synthesis of metabolites of Bentazon (B120580), a selective post-emergence herbicide.

Applications Adenose N-Oxide and its derivatives are used as an active ingredient in the preparation of therapeutic agents for inflammatory diseases and inhibitors of adenosine kinase.
References Long, M. & Parker, W.: Biochem. Pharmacol., 71, 1671 (2006)

Applications 2,4-Dichloro-5-nitropyrimidine (cas# 49845-33-2) is a compound useful in organic synthesis.

Applications 4-Chlorobutanoic acid methyl ester is used as a precursor chemical for projects such as vapor deposition for attaching ionic liquid to oxide surfaces1 and the synthesis of new thiopyran-​based heterocyclic systems2.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Xu, W., et al.: Angew. Chem. Int Ed., 56, 9072-9076. (2017)2. Palchykov, V.A., and al.: New J. Chem., 42, 1403 - 1412 (2018)

Applications Guanosine 3’-O-Tetraisopropyldisiloxyanyl Ether is an isotope labelled intermediate in the preparation of nucleotide analogs.
References Robins, M. J., et al.: J. Am. Chem. Soc., 105, 4059 (1983);

Applications N,N-Dimethyl-2,4-dinitro-1-naphthalenamine (cas# 39139-79-2) is a compound useful in organic synthesis.

Applications Tetrahydro-2-(2-nitropropoxy)-2H-pyran (cas# 97945-38-5) is a compound useful in organic synthesis.

Applications tert-Butyldimethylsilyloxy-5-aza-2'-deoxycytidine is an intermediate in the synthesis of metabolites of Azadeoxycytidine (A796950), as neoplasm inhibitor.
References Cihak, A., et al.: Eur. J. Cancer, 14, 117 (1978),

Applications Intermediate in the synthesis of a cholesterol absorption inhibitor.
References Kambara, T. et al.; J. Org. Chem. 64, 9282 (1999); Wu, G. et al.; J. Org. Chem. 62, 6412 (1997)

Applications Intermediate for the synthesis of 9-cis-Retinoids
References Rosen, J., et al.: J. Med. Chem., 38, 4855 (1995), Haupt, U., et al.: Biochem., 36, 2 (1997).

Applications 10,11-Dihydrobenz[a]anthracene is an intermediate in the synthesis of phenols of Benz[a]anthracene (B183560).
References Fu, P.P.,e t al.: J. Org. Chem, 44, 4265 (1979)

Applications Propylene Glycol 2-β-Glucopyranosiduronic Acid Benzyl Ester-d6 is an intermediate in the synthesis of Isotope labelled Propylene Glycol 2-Glucuronide which is a metabolite of propylene glycol, used in the synthesis of N-terminal kinase inhibitors with cellular activity. Acts as a solvent for various pharmaceutical compounds.
References Szczepankiewicz, B. et al.: J. Med. Chem., 49, 3563 (2006); Mateus, R. et al.: Int. J. Pharm., 444, 106 (2013);

Applications 2-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)acetyl]-butanedioic-2-13C Acid Diethyl Ester is an intermediate in the synthesis of 5-Aminolevulinic Acid-3-13C Hydrochloride which is a naturally occurring amino acid; precursor of tetrapyrroles in the biosynthesis of chlorophyll and heme. Antineoplastic (photosensitizer).
References Sisler, E.C., et al.: Physiol. Plant., 16, 315 (1963), Herdeis, C., et al.: Arch. Pharm., 317, 304 (1984), Peng, Q., et al.: Cancer, 79, 2282(1997),

Applications Phinothricin metabolite.
References Komossa, D. et al.: Pestic. Biochem. Phys. 43, 95 (1992)

Applications 2-Bromo-3'-hydroxyacetophenone (cas# 2491-37-4) is a compound useful in organic synthesis.

Applications N-(2-Hydroxy-4-nitrophenyl)phthalimide (cas# 117346-07-3) is a compound useful in organic synthesis.

Applications (R)-(-)-Norlaudanosine N-5-Hydroxypentyl Propionate is an intermediate in synthesizing N-Desmethyl-transatracurium Besylate (D295480), a structural analogue of Atracurium Besylate (A794500), A neuromuscular blocking agent.
References Hughes, R., et al.: Br. J. Anaesth., 53, 31 (1981), Basta, S.J., et al.: Anesth. Analog., 61, 723 (1982), Neill, E.A., et al.: Xenobiotica, 12, 203 (1982)

Applications A deuterated acyclic phosphonate nucleotide.

Applications 5-Chloro-1,2-dihydro-1-acenaphthylenol is used in the preparation of benzimidazole derivatives as receptor agonists for the treatment of central nervous system diseases.

Stability Temperature Sensitive
Applications This compound contains 10-20% of the alpha isomer. The exact amount has not been quantified.

Applications Cinnamyl Bromide acts as a reagent in the synthesis of Arylpiperidines as a new class of oxidosqualene cyclase inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Keller, M., et al.: Eur. J. Med. Chem., 109, 13 (2016)

Applications DL-10-Camphorsulfonyl Chloride is used as a the starting material in the synthesis of 10-Camphorsulfonic Acid Ethyl Ester (C175040). It is also used as a reagent in the synthesis of 1-benzhydrylpiperazine derivatives which can exhibit antiproliferative activity in vitro against human cancer cell lines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ananda Kumar, C.S., et al.: Eur. J. Med. Chem., 44, 1223 (2009)

Applications A 9-substituted derivative of the polycyclic aromatic hydrocarbon (PAH) Anthracene (A678400).

Applications Intermediate for the synthesis of neuromuscular blocking agents.

Applications 2-Acetamido-3-acetoxybenzoic Acid Methyl Ester is an intermediate in the synthesis of metabolites of Bentazon (B120580), a selective post-emergence herbicide.

Applications 9,10-Dichloro-2,6-dimethylanthracene (cas# 887354-46-3) is a compound useful in organic synthesis.

Applications α-(Dibutylamino)-4-methoxy-benzeneacetic Acid is an intermediate in the synthesis of Ambucetamide (A575935). Ambucetamide is an antispasmodic found to be particularly effective for the relief of menstrual pain.
References Janssen, P., et al.: J. Am. Chem. Soc., 76, 6192 (1954); Pickles, V., et al.: 15, 128 (1960)

Applications 1,3-Dihydro-N-nitro-1,3-dioxo-2H-isoindole-2-carboximidothioic acid Methyl Ester-13C is an intermediate used in the synthesis of Clothianidin-d3,13C1 (C588502), which is the isotope labelled analog of Clothianidin. Clothianidin is a neonicotinoid insecticide for use in food crops.
References Kamel, A., et al.: J. Agric. Food Chem., 58, 5926 (2010), Lynd, L., et al.: Energy Environ. Sci., 3, 1150 (2010), Cresswell, J., et al.: Ecotoxicology, 20, 149 (2011),

Applications N,​N-​Dimethyl-​5-​(phenylmethoxy)​-1H-​indole-​3-​ethan-​α,​α,​β,​β-​d4-​amine is an intermediate in the synthesis of Bufotenine-d4 Hydrochloride (B689467), which is labelled bufotenine Hydrochloride (B689465) which is a weak hallucinogenic agent active by intravenous injection. It is a constituent of toad poison.
References Stoll, et al.: Helv. Chim. Acta, 38, 1452 (1955), Bhattacharya, S., et al.: Indian. J. Physiol. Pharmacol., 15, 133 (1971), Falkenberg, G., et al.: Acta Crystallogr., 28B, 3219 (1972)

Applications (5-Chloro-2-nitrophenyl)(phenyl)carbamic Acid tert-Butyl Ester is an intermediate in the synthesis of Clobazam (C582500), a benzodiazepine psychotherapeutic agent and anxiolytic agent.

Applications 2-Hydroxy-5-benzyloxyacetophenone (cas# 30992-63-3) is a compound useful in organic synthesis.

Applications 1-[(4-Chlorophenyl)methyl]-2-oxocyclopentanecarboxylic Acid Methyl Ester is an intermediate in the synthesis of Isotope labelled Metconazole (M225795), an conazole based fungicide used for the control of black sigatoka disease on banana.
References Kato, A., et al.: Chem. Pharma. Bull., 43, 2152 (1995);

Applications 8-Bromo-3’,5’-Di-O-tert-butyldimethylsilyl-2’-deoxyguanosine is a compound useful in organic synthesis.

Applications N'-[(2-Chloro-5-thiazolyl)methyl]-N-nitro-carbamimidothioic Acid Methyl Ester-13C is an intermediate used in the synthesis of Clothianidin-d3,13C1(C588502), which is the isotope labelled analog of Clothianidin. Clothianidin is a neonicotinoid insecticide for use in food crops.
References Kamel, A., et al.: J. Agric. Food Chem., 58, 5926 (2010), Lynd, L., et al.: Energy Environ. Sci., 3, 1150 (2010), Cresswell, J., et al.: Ecotoxicology, 20, 149 (2011),

Applications 6-Methyl-5-(phenylmethoxy)-3,4-pyridinedicarboxylic Acid is an intermediate in synthesizing 5-Hydroxy-6-methyl-3,4-pyridinedicarboxylic Acid (H946970), which is used in studies to identify 4-pyridoxic acid dehydrogenase gene in pyridoxine catabolism of Mesorhizobium loti MAFF303099.
References Mukherjee, T., et al.: Bioorg. Chem., 35, 458 (2007)

Applications Used in the preparation of labeled cocaine analogs.
References Carroll, F.I., et al.: J. Med. Chem., 35, 2497 (1992),

Applications 3-Aminobenzoic-d4 Acid (A591492) derivative. It increases attractiveness when combines with sex pheromones.
References Maekawa, M. et al.: Appl. Entomol. Zool., 34, 9 (1999)

Applications 5-Bromo-2',3',5'-tri-O-acetyluridine (cas# 105659-32-3) is a compound useful in organic synthesis.

Applications (S)-2-(Acetylthio)-propanoic Acid is an intermediate in synthesizing (R)-(+)-Thiolactomycin (T350880). It is a natural product inhibitor of β-Ketoacyl-AcpM Synthase A (KasA). It inhibits the synthesis of mycolic acid which is a major cell wall component of Mycobacterium tuberculosis. Also an inhibitor of D-Aspartate oxidase (DDO).
References Kapilashrami, K., et al.: J. Biol. Chem., 288, 6045 (2013); Paneerselvam, V., et al.: J. Pharm. Res., 4, 4618 (2011); Katane, M., et al.: Biochimie, 92, 1371 (2010)

Applications 1,1,3,3-Tetraethylurea is a useful building block for organic synthesis.

Applications 5’-Deoxy-5’-iodo-2’,3’-O-isopropylidene-5-fluorouridine-13C,15N2 >95% is a compound useful in organic synthesis.

Stability Light Sensitive
Applications Retinyl Retinoate is used in the treatment of skin diseases and disorders such as acne, psoriasis and photoaging.
References Kim, B. et al.: Int. J. Derm., 51, 733 (2012); Kim, J. et al.: Brit. J. Derm., 162, 497 (2010);

Applications D-Aspartic Acid-d3 L-Alanine Copper(II) Complex is an intermediate in the synthesis of D-Aspartic-2,3,3-d3 Acid (A790019) which is derived from D-Asparatic Acid (A790020), which is a non-essential amino acid found in food sources. Its conjugate base D-aspartate has potential use as an therapeutic agent in the treatment of schizophrenia-related symptoms.
References Errico, F. et al.: J. Neurosci., 28, 10404 (2008); Denu, J.M. et al.: Biochem., 34, 3396 (1995); Chen, P.E. et al.: Mol. Pharmacol., 67, 1470 (2005);

Applications 3-Chloronaphthalene-2,7-disulfonyl Dichloride is an intermediate used in the synthesis of 2,3,6-Trichloronaphthalene (T774070), which can bind to the aryl hydrocarbon receptor (AhR) and induce a wide range of pleotrophic effects.
References Petrulis, J., et al.: Toxicol. Lett., 105, 251 (1999), Hilscherova, K., et al.: Environ. Sci. Pollut. Res., 7, 159 (2000),

Applications cis-Dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.13,7]decane]-4-acetic Acid is an intermediate for the synthesis of Arterolane p-Toluenesulfonic Acid (A614161), which is an antimalaria agent.
References Valecha, N., et al.: Clin Infect Dis. 55, 663 (2012); Patil, C. Y., et al.: Ann Med Health Sci Res. 4, 466 (2014)

Applications Intermediate in the synthesis of polycyclic aromatic systems.

Applications (4S-cis)-4-(O-TBDMS-1-methylethyl)-2,2,5-trimethyl-1,3-dioxolane-4-carboxylic Acid is an intermediate in the synthesis of (+)-Echimidine N-Oxide, which is a hepatotoxic pyrrolizidine alkaloid. Different extracts and echimidine-N-oxide from Symphytum sylvaticum Boiss. Subsp. sepulcrale, has been shown to have Antifungal activity.
References Kartal, M., et al.: Turkish, J. Med. Sci., 31, 487 (2001); Cao, Y., J. Food Comp. Anal., 29, 106 (2013);

Applications 4-(Ethoxycarbonyl)phenyl 2,3,4-Triacetate β-D-Glucopyranosiduronic Acid Methyl Ester is an intermediate in the synthesis of p-Salicylic Acid 4-Glucuronide which is an anthocyanin-derived phenolic acid degraded to form 4' glucuronide of 4-hydroxybenzoic acid during simulated gastrointestinal digestion and in human liver microsome.
References Zhang, Q.Z., et al.: Tetrahedron/, 68l, 4194 (2012); Woodward, G.M., et al.: Molec. Nutrition. Food. Res., 55, 378 (2011);

Applications α-(Phenylmethylene)-1-naphthaleneacetic Acid is an intermediate in the synthesis of chrysene based polycyclic aromatic ketones found in environmental gas samples of wood and coal combustion gasses, municipal incineration waste gases, diesel exhaust, Al plant workplace and urban ambient air.
References Dai, W., et al.: Org. Prep. Proc. Int., 29, 347 (1997);

Applications (S)-2-(Dimethoxymethyl)-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester is an intermediate in synthesizing Tilivalline (T440350), which is a metabolite from Klebsiella oxytoca. Tilivalline, is shown to be cytotoxin, and the key event causing Antibiotic-Associated Hemorrhagic Colitis.
References Mori, Sh., et al.: Tetrahedron, 47, No.27, 5051 (1991); Nagasaka, T., et al.: Tetrahedron Lett., 14, 1871 (1989);

Applications 7-Chloro-1,3-naphthalenedisulfonic Acid is an intermediate in synthesizing 1,3,7-Trichloronaphthalene (T774065). Chloronaphthalenes (CNs) can bind to the aryl hydrocarbon receptor (AhR) and induce a wide range of pleotrophic effects.
References Petrulis, J., et al.: Toxicol. Lett., 105, 251 (1999), Hilscherova, K., et al.: Environ. Sci. Pollut. Res., 7, 159 (2000)

Applications 2-Isopropenyl-5-methyl-4-hexenoic Acid Ethyl Ester is an intermediate in the synthesis of (±)-Lavandulyl Acetate (L200000), a component of lavender oil.
References Pepper, H, P., et al.: J. Org. Chem., 79, 2564 (2014);

Applications 3-Iodopropylene-1-naphthalene Methyl Amine (cas# 1076198-32-7) is a compound useful in organic synthesis.

Applications 9-Chlorophenazine-1-carboxylic Acid is an intermediate in the synthesis of Endophenazine A which is a new phenazine antibiotic isolated from the arthropod associated endosymbiont Streptomyces anulatus and shows antimicrobial activities against Gram-positive bacteria and some filamentous fungi, and herbicidal activity against Lemna minor (duckweed).
References Gebhardt, K., et al.: J. Antibiot., 55, 794 (2002)

Applications N-METHYLTHIOUREA (cas# 598-52-7) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Impurity Vonoprazan Impurity 31
Applications 2'-Fluoroacetophenone (Vonoprazan Impurity 31)

Applications Tetrabromophthalic Anhydride-13C6 is an intermediate in synthesizing 2,3,4,5-Tetrabromobenzoic Acid-13C6 (T291142). It is an isotope labelled analog of 2,3,4,5-Tetrabromobenzoic Acid. 2,3,4,5-Tetrabromobenzoic Acid is an in vitro metabolite of the flame retardant 2-Ethylhexyl 2,3,4,5-Tetrabromobenzoate (E918780) in human and rat tissues.
References Roberts, S.C., et al.: Chem. Res. Toxicol., 25, 1435 (2012); Gouteux, B., et al.: Environ. Sci. Technol., 42, 9039 (2008); Lee, E., et al.: J. Toxicol. Sci., 2010, 35, 535 (2010); Arp, H., et al.: J. Environ. Monit., 13, 505 (2011)

Applications (cas# 1993-11-08) is a useful research chemical.

Applications 2'-(Methylamino)-5'-nitro-succinanilic Acid is an intermediate in synthesizing 4-(6-(2-Chloroethyl)-3-methyl-3,6,7,8-tetrahydroimidazo[4',5':5,6]benzo[1,2-b][1,4]thiazin-2-yl)butanoic Acid (C367195), a degradation production of Bendamustine (B132500), which is used as an anticancer drug.
References Bremer, K., et al.: Tumordiagn. Ther., 17, 1 (1996); Barman Balfour, J.A., et al.: Drugs, 61, 631 (2001)

Applications 2,4,5-Trichlorophenoxyacetic Acid-d5 is an isotope labelled analog of 2,4,5-Trichlorophenoxyacetic Acid. It is suitable for plant cell culture tested. Post-emergence herbicide.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Smith, J., et al.: Science, 203, 1090 (1979), Salunkhe, C., et al.: Plant Cell Reports, 18, 670 (1999), Jheng, F., et al.: Plant Sci., 170, 1133 (2006),

Applications N-​(Methoxycarbonyl)​-L-​glutamic Acid 5-​Ethyl Ester is an intermediate in synthesizing (S)-Vigabatrin (V253000), a novel anti-epileptic drug. Antidepressant; antipsychotic; anxiolytic.
References Vajda, F., et al.: Clin. Neurosci., 7, 88 (2000); Beghi, E., et al.: Lancet. Neurol., 3, 618 (2004); Sagirli, O., et al.: J. Pharmaceut. Biomed., 42, 618 (2006);

Applications [1,1'-Binaphthalen]-8-ol is an intermediate in the synthesis of Benzo[j]fluoranthene (B205690), a polycyclic aromatic hydrocarbon that has tumour initiating activity and can be found in soot, oil, water and soil extracts as a common pollutant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Rice, J. E., et al.: J. Org. Chem., 58, 1415 (1993);

Applications Intermediate for the preparation of Nitrazepam.

Applications 2’,3’,5’-Tri-O-acetyl Guanosine-13C2,15N is an intermediate in the synthesis of 8-Aminoguanosine-13C2,15N (A609877). 8-Aminoguanosine-13C2,15N is an isotopic labelled compound of 8-Aminoguanosine (A609875), which is a potent inhibitor of purine nucleoside phosphorylase.
References Kazmers, I.S., et al.: Science, 214, 1137 (1981); Chern, J-W., et al.: J. Med. Chem., 36, 1024 (1993)

Applications 2,4-Dibromo Deuteroporphyrin IX Dimethyl Ester is an intermediate for the synthesis of Protoporphyrin IX Dimethyl Ester-d6 (P839127), which is the labelled version of Protoporphyrin IX P(P838900). Protoporphyrin IX (PPIX) is ubiquitously present in all living cells in small amounts as a precursor of heme and PPIX-based strategies have been used for cancer diagnosis and treatment. It can be used in biological study for role of protoporphyrin IX in skin photosensitivity, biliary stones, hepatobiliary damage, liver failure and cancer diagnosis and treatment in human.
References Sachar, M., et al.: J. Pharmacol. Exp. Ther., 356, 267-275 (2016)

Applications Dichloroacetic Acid Methyl Ester is used in the preparation of telechelics and block copolymers through living radical polymerization.
References Keul, H., et. al.: Macromol. S., 19, 1 (1971)

Applications O6-Benzyl-8-bromo-N9-[3’,5’-O-(1,1,3,3-tetrakis(isopropyl)-1,3-disiloxanediyl)-β-D-2’-deoxyribofuranosyl]guanine (cas# 328394-26-9) is a compound useful in organic synthesis.

Applications 7-(Dimethylamino)-4-methylcoumarin (cas# 87-01-4) is a useful research chemical.

Applications 4,6-Bis(4-nitrophenoxy)pyrimidine is an intermediate in the synthesis of N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N'-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea (E926495), which is an inhibitor of RET, FLT3, KDR, c-Abl and c-Kit. Also, it prevent the growth of human thyroid cancer cells.
References Weisberg, E., et al.: Genes Cancer, 1, 1021-1032 (2010);

Applications 2,3,4-Trihydroxyacetophenone is used as a reagent in the synthesis of chromenone and quinolinone derivatives as potent antioxidant agents.
References Vats, P., et al.: Med. Chem. Res., no vol., no pp. (2014)

Applications (2R,4R)-2-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-4-hydroxy-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of 2’-epi-Lincomycin which is an epimer of Lincomycin (L466200) which is a 6-amino, 6-deoxy-octopyraninose with strong antibiotic activity.
References Le Goffic, F. et al.: J. Antimicrob. Chemother., 16, 12 (1985); Prior, C. et al.: J. Pharmacol. Exp. Therap., 255, 1170 (1990)

Applications 5-Chloro-2-methoxy-1,3-benzenedicarboxylic Acid is an intermediate in the synthesis of Ochratoxin A (O148490). Ochratoxins are toxic metabolites from Aspergillus ochraceus. Also they are environmental and food contaminants.
References Belli, N., et al.: Int. J. Food Microb., 96, 19 ( 2004); Pardo, E., et al.: Food Microb., 23, 35 (2006)

Applications (2E)​-5-​[3-​[2-​(3,​3-​Dimethyl-​2-​oxiranyl)​ethyl]​-​3-​methyl-​2-​oxiranyl]​-​3-​methyl-​2-​pentenoic-d3 Acid is a by-product during the synthesis of trans-trans-10,11-Epoxy Farnesenic Acid-d3 Methyl Ester (E589402), a labelled trans-trans-10,11-Epoxy Farnesenic Acid Methyl Ester (E589400). trans-trans-10,11-Epoxy Farnesenic Acid Methyl Ester is a metabolite (2E,6E)-Farnesenic Acid.
References Koeppe, J., et al.: J. Biol. Chem., 259, 3219 (1984); King, L., et al.: Insect. Biochem., 18, 793 (1988); Park, Y., et al.: Biochemistry, 32, 7909 (1993)

Stability Hygroscopic
Applications Dihydroxyacetone Phosphate Lithium Salt, is a metabolic intermediate involved in involved in a wide variety of metabolic pathways including glycolysis and lipid biosynthesis. In plants, Dihydroxyacetone phosphate is involved with the synthesis of vitamin B6.
References Jun Ogawa et. al.: et al.: Bioscience, biotechnology, and biochemistry, 67(4), undefined (2003-6-6); John P Richard, Biochemistry, 51(13), undefined (2012-3-14);

Stability Readily Polymerizes
Applications A precursor of polynuclear aromatic hydrocarbons in tobacco smoke.

Applications 2-Bromovaleric acid

Applications A highly reactive thiol-specific spin-label. A specific conformational probe of thiol site structure by virtue of its minimal rotational freedom and distance from the covalent disulfide linkage to the macromolecule under study.

Boc-L-tyrosine N-hydroxysuccinimide ester is a linker that is used for the synthesis of peptides. It has good solubility in dimethylformamide and can be incorporated into synthetic peptides. Boc-L-tyrosine N-hydroxysuccinimide ester reacts with lysine residues to form amide bonds, which are stable under physiological conditions. It also has a hydroxy group that can be used to conjugate other molecules. This linker has been used in vitro studies and clinical trials, as well as for the preparation of peptidyl conjugates for histological analysis.

5-Iodocytosine (5-IC) is an analog of cytosine that can be used as a precursor for the synthesis of thymine. 5-IC has been shown to cross-couple with DNA, which may contribute to its antiviral potency. 5-IC is also a potent inhibitor of dna replication and herpes simplex virus. The biochemical properties of 5-IC have been extensively studied, including its ability to react with hydrochloric acid to form the corresponding tautomers. The hydrolysis rate increases at higher pH values and decreases at lower pH values. Bioconjugate chemistry has been applied to synthesize a bioconjugated prodrug of 5-IC for cancer treatment.