Inibitori
Gli inibitori sono molecole che si legano a enzimi, recettori o altre proteine per ridurre o bloccare la loro attività biologica. Questi composti sono ampiamente utilizzati nella ricerca per studiare le vie biologiche, comprendere i meccanismi delle malattie e sviluppare farmaci terapeutici. Gli inibitori svolgono un ruolo cruciale nel trattamento di varie malattie, tra cui il cancro, le malattie cardiovascolari e le infezioni. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità per supportare le tue ricerche in biochimica, biologia cellulare e sviluppo farmaceutico.
Sottocategorie di "Inibitori"
- Angiogenesi(2.805 prodotti)
- Apoptosi(6.292 prodotti)
- Ciclo cellulare/Checkpoint(4.820 prodotti)
- Cromatina/Epigenetica(2.490 prodotti)
- Segnalazione citoscheletrica(1.544 prodotti)
- Danno al DNA/Riparazione del DNA(2.940 prodotti)
- Endocrinologia/Ormoni(3.706 prodotti)
- Enzima(3.670 prodotti)
- Proteina G/GPCR(9.024 prodotti)
- Immunologia e infiammazione(3.902 prodotti)
- Virus dell'influenza(302 prodotti)
- Segnalazione JAK/STAT(417 prodotti)
- Segnalazione MAPK(1.247 prodotti)
- Trasportatore di membrana/canale ionico(3.078 prodotti)
- Metabolismo(10.178 prodotti)
- Microbiologia/Virologia(7.618 prodotti)
- Neuroscienza(10.367 prodotti)
- Altri inibitori(35.951 prodotti)
- Ossidazione-riduzione(41 prodotti)
- Segnalazione PI3K/Akt/mTOR(1.442 prodotti)
- Proteasi/Proteasoma(1.716 prodotti)
- Cellule staminali e Derivati(801 prodotti)
- Adattatori Tirosin-chinasi(2.030 prodotti)
- Ubiquitinazione(1.722 prodotti)
Mostrare 16 più sottocategorie
Trovati 66630 prodotti di "Inibitori"
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Hymenidin
CAS:Hymenidin, isolated from the Okinawan sponge Hymeniacidon sp., is a 5-hydroxytryptaminergic receptor antagonist and voltage-gated potassium channel inhibitor.Formula:C11H12BrN5OPurezza:96.85% - 99.52%Colore e forma:SolidPeso molecolare:310.15N-methyl Leukotriene C4
CAS:N-methyl LTC4 is a stable synthetic analog of LTC4 and a selective CysLT2 agonist, useful in studying leukotriene pharmacology.Formula:C31H49N3O9SColore e forma:SolidPeso molecolare:639.8FGFR4-IN-7
FGFR4-IN-7 is a covalent, reversible FGFR4 inhibitor (IC50: 0.42 μM) that blocks the FGFR4 signaling pathway, thereby inducing apoptosis.Formula:C26H25Cl2N5O3Colore e forma:SolidPeso molecolare:526.41Tovinontrine
CAS:Tovinontrine (IMR-687) (IMR-687) is a potent and selective inhibitor of phosphodiesterase-9 (PDE9), designed to target sickle cell disease treatment.Formula:C21H26N6O2Purezza:98.8%Colore e forma:SolidPeso molecolare:394.47PTP1B-IN-18
PTP1B-IN-18 is an orally active, fully mixed protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 35.2 μM).PTP1B-IN-18 can be used to study type 2 diabetes.Formula:C26H19N3O4SColore e forma:SolidPeso molecolare:469.51BMT-052
CAS:BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).Formula:C30H17D9F4N6O5Purezza:98%Colore e forma:SolidPeso molecolare:635.61c(phg-isoDGR-(NMe)k)
CAS:c (phg-isoDGR- (NMe) k) is a selective and effective α5β1-integrin ligand with IC50 of 2.9 nM.Formula:C27H41N9O7Purezza:98%Colore e forma:SolidPeso molecolare:603.67DS89002333
DS89002333: oral PRKACA inhibitor with 0.3 nM IC50, effective against FL-HCC with DNAJB1-PRKACA fusion in xenografts.Formula:C22H20ClF2N3O3Colore e forma:SolidPeso molecolare:447.86K20
K20 selectively inhibits KRas G12C (IC50: 1.16 nM), shows anticancer activity in H358 cells (IC50: 0.78 μM), and induces apoptosis via Erk dephosphorylation.Formula:C24H20Cl2F4N4O2Colore e forma:SolidPeso molecolare:543.34DNA gyrase B-IN-1
DNA gyrase B-IN-1, a potent inhibitor of P. aeruginosa DNA gyrase B, has IC50 of 2.2 μM with high affinity and stability.Formula:C23H18ClF3N6O4SColore e forma:SolidPeso molecolare:566.94NA 0362
CAS:NA 0362 is a derivative of SF 2370 that inhibits smooth muscle contraction.Formula:C28H26N4O4Colore e forma:SolidPeso molecolare:482.53PF-4693627
CAS:PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM).Formula:C26H29Cl2N3O3Purezza:98%Colore e forma:SolidPeso molecolare:502.43CBR Agonist-2
CBR Agonist-2: CB1 receptor agonist, EC50 - 960 nM, Ki - 970 nM, useful for hCB1R-related disease research.Formula:C27H27FN4OColore e forma:SolidPeso molecolare:442.53KC-11404
CAS:KC-11404 is an LTB4 inhibitor for the treatment of b-cell leukemias and lymphomas, potently inhibiting histamine, platelet activating factor and 5-lipoxygenase.Formula:C28H38N4OColore e forma:SolidPeso molecolare:446.63TTT 3002
CAS:TTT 3002: oral FLT3 inhibitor for AML research, blocks D835 mutations, potent at 0.2 nM IC50.Formula:C27H23N5O3Colore e forma:SolidPeso molecolare:465.50VVD-118313
CAS:VVD-118313 (5a) is a potent JAK1 inhibitor targeting allosteric cysteine, blocking cytokine signaling for cancer research.Formula:C19H22Cl2N2O3SColore e forma:SolidPeso molecolare:429.36Fonsartan free acid
CAS:Fonsartan: Angiotensin receptor blocker, halts angiotensin II effects on rat vascular cells.Formula:C26H32N4O5S2Purezza:98%Colore e forma:SolidPeso molecolare:544.69HIF-1α-IN-5
HIF-1α-IN-5 is an inhibitor of HIF-1α with an IC 50 value of 24 nM in HEK293T cells that also inhibits the activity of MAO-A.Formula:C16H15N3O2Colore e forma:SolidPeso molecolare:281.31E6201
CAS:E6201, a dual kinase inhibitor, blocks MEK1/FLT3 and has anti-tumor/psoriasis effects with low IC50s: ERK2 (5.2 nM), JNK (91 nM), p38 MAPK (19 nM).Formula:C21H27NO6Colore e forma:SolidPeso molecolare:389.44MTL-CEBPA
MTL-CEPBA is a small activating RNA that targets C/EBPα upregulation and exhibits anti-inflammatory and anti-cancer effects.Colore e forma:SolidFumarranol
CAS:Fumarranol inhibits angiogenesis and malaria growth by targeting PfMAP2.Formula:C16H24O4Colore e forma:SolidPeso molecolare:280.36Ro 24-4383
CAS:Ro 24-4383 is a carbamate-linked dual-action antibacterial agent.Formula:C32H31FN8O10S2Purezza:98%Colore e forma:SolidPeso molecolare:770.76ATX inhibitor 12
Oral ATX inhibitor 12 (IC50: 1.72 nM) at 60 mg/kg prevents lung damage in C57Bl/6J mice.
Formula:C30H34FN5O2Colore e forma:SolidPeso molecolare:515.62KRAS G12C inhibitor 37
CAS:KRAS G12C inhibitor 37 targets a key signaling protein, showing promise for cancer research involving KRAS G12C.Formula:C35H39F3N8O2Colore e forma:SolidPeso molecolare:660.73AKT-IN-10
CAS:AKT-IN-10, a potent AKT inhibitor, has potential for breast and prostate cancer research, impacting cell growth and survival pathways.Formula:C26H34ClN5O2Colore e forma:SolidPeso molecolare:484.03BACE1-IN-2
CAS:BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).Formula:C19H15F4N5O2Purezza:98%Colore e forma:SolidPeso molecolare:421.35S1PR1 agonist 1
CAS:S1PR1 agonist 1 is a potent agonist of S1PR1. S1PR1 agonist 1 has potential in autoimmune diseases.
Formula:C29H30N4O4Colore e forma:SolidPeso molecolare:498.57Antileishmanial agent-5
Antileishmanial agent-4, a ribonucleoside analogue, targets L.infantum and T.cruzi with EC50s of 0.68 μM and 0.83 μM.Formula:C17H17ClN4O4Colore e forma:SolidPeso molecolare:376.79Anti-inflammatory agent 9
Benzimidazothiazole-derived Compound 28 from tilomisole targets COX-2, has potent anti-inflammatory effects & is orally bioavailable.Formula:C18H15N5O2SColore e forma:SolidPeso molecolare:365.41GNE-886
CAS:GNE-886 has a wide range of applications in life science related research.Formula:C28H30N6O3Purezza:98%Colore e forma:SolidPeso molecolare:498.59CDK2-IN-9
CDK2-IN-9: potent CDK2 inhibitor (IC50: 0.63 μM), anti-proliferative, arrests S/G2M cell cycle, induces apoptosis, promising for melanoma study.Formula:C21H16ClN3O4SColore e forma:SolidPeso molecolare:441.89CHK1-IN-2
CAS:CHK1-IN-2 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 6 nM).Formula:C20H22N4OSPurezza:98%Colore e forma:SolidPeso molecolare:366.48Aurora A inhibitor 1
CAS:Aurora A inhibitor 1: potent, selective, targets cancer-linked Aurora A overexpression, potential for cancer research. (WO2021147974A1, 49)Formula:C25H28ClF2N5O2Colore e forma:SolidPeso molecolare:503.97ZK824859 hydrochloride (2271122-53-1 free base)
ZK824859 hydrochloride: oral, selective uPA inhibitor, IC50s: 79 nM (uPA), 1580 nM (tPA), 1330 nM (plasmin).Formula:C23H23ClF2N2O4Purezza:98%Colore e forma:SolidPeso molecolare:464.89PAIR2
CAS:PAIR2 is a selective IRE1α RNase partial antagonist, blocking its ATP site and preventing KIRA from hindering XBP1 splicing.Formula:C27H26F4N6O3SColore e forma:SolidPeso molecolare:590.59NPR-C activator 1
CAS:NPR-C activator 1 is an activator of the natriuretic peptide receptor C (NPR-C), which can be used to study cardiovascular diseases.Formula:C18H24N6O3Purezza:98.74%Colore e forma:SolidPeso molecolare:372.42RdRP-IN-4
RdRP-IN-4, an oral arylbenzohydrazide, inhibits influenza A/B by targeting PB1 of RdRP, with EC50s of 53 nM (H1N1) and 20 nM (Flu B), and aids infected mice.Formula:C17H17Br2N3O2Colore e forma:SolidPeso molecolare:455.144'-Ethynyl-2'-deoxyadenosine
CAS:4'-E-dA is a potent nucleoside RT inhibitor for drug-resistant HIV (EC50: 98 nM in MT-4 cells).Formula:C12H13N5O3Purezza:98%Colore e forma:SolidPeso molecolare:275.26LpxA-IN-1
CAS:LpxA-IN-1, a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor exhibiting potent activity (IC 50 2 nM), effectively targets Pseudomonas aeruginosaFormula:C21H11D7F3N5O3Colore e forma:SolidPeso molecolare:452.44DJT06001
CAS:DJT06001 is a selective Factor Xa inhibitor, reducing thrombus formation with low risk of bleeding.Formula:C21H20ClN3O5SColore e forma:SolidPeso molecolare:461.92PIKfyve-IN-1
PIKfyve-IN-1: potent, cell-active inhibitor for PIKfyve research, IC50=6.9 nM.Formula:C20H21N5Colore e forma:SolidPeso molecolare:331.41Cdc7-IN-18
CAS:Cdc7-IN-18 (1-2) inhibits CDC7 enzyme (IC50: 1.29 nM) and COLO205 cell proliferation (IC50: 53.62 nM).Formula:C19H21N5OSColore e forma:SolidPeso molecolare:367.47PTP1B-IN-21
PTP1B-IN-21 inhibits PTP1B (IC50=1.56μM) selectively over TCPTP, a type 2 diabetes target.Formula:C22H22O11Colore e forma:SolidPeso molecolare:462.4Cas9-IN-1
Cas9-IN-1 is a potent inhibitor of Cas9 with an IC50 value of 7.02 μM. Cas9-IN-1 acts by binding apo-Cas9 and blocking the formation of the Cas9:gRNA complex.Formula:C17H11Cl2F3N2O3SColore e forma:SolidPeso molecolare:451.25Rivenprost
CAS:Rivenprost, selective EP4 agonist (Ki: 0.7 nM), promotes bone growth, osteoblast differentiation, and aids wound healing.Formula:C24H34O6SColore e forma:SolidPeso molecolare:450.59PRMT5-IN-21
PRMT5-IN-21 (compound 1) is a potent inhibitor of cyclonucleoside PRMT5.Formula:C18H18F2N6O3Colore e forma:SolidPeso molecolare:404.37Antiviral agent 6
Antiviral agent 6 showed excellent anti-TSWV effects in vivo (EC50: 188 mg/L).Formula:C23H27BrN2O3S2Colore e forma:SolidPeso molecolare:523.51Nomelidine
CAS:Nomelidine, the active N-demethylated metabolite of zimelidine, has been used as an antidepressant and analgesic.Formula:C15H15BrN2Purezza:98%Colore e forma:SolidPeso molecolare:303.20PqsR-IN-1
PqsR-IN-1, potent PqsR inhibitor, curbs pyocyanin in Pseudomonas aeruginosa with low cytotoxicity.Formula:C17H18ClN3OSColore e forma:SolidPeso molecolare:347.86MraY-IN-3
MraY-IN-3 (12a) is a potent inhibitor of the bacterial translocase MraY (IC50: 140 μM). 46 μg/ml).Formula:C35H45N3O5Colore e forma:SolidPeso molecolare:587.75Cav 3.2 inhibitor 1
Cav 3.2 inhibitor 1 targets T-type calcium channels, weakly binds D2 receptors, and aids physical and visceral pain research.Formula:C32H39N3OColore e forma:SolidPeso molecolare:481.67PptT-IN-2
PptT-IN-2 inhibits PptT enzyme crucial in tuberculosis, with 2.5 μM IC50, showing potential in TB research.Formula:C22H29N5O2Colore e forma:SolidPeso molecolare:395.5Hypothemycin
CAS:Hypothemycin, a fungal polyketide, inhibits multiple kinases (VEGFR, MEK, FLT-3, PDGFR, ERK) with Kis ranging from 10 nM to 2.4 μM.Formula:C19H22O8Purezza:98%Colore e forma:SolidPeso molecolare:378.37Anticancer agent 80
Anticancer agent 80 (Compound 3c) is an anticancer agent that exhibits a significant dark toxic effect on T47-D (IC50: 10.14 μM).Formula:C19H12BrNO5Colore e forma:SolidPeso molecolare:414.21LY309887
CAS:LY309887 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (Ki: 6.5 nM). It also has antitumor activity.Formula:C19H23N5O6SColore e forma:SolidPeso molecolare:449.48KRAS G12C inhibitor 44
KRAS G12C inhibitor 44: potent, oral, anti-cancer; halts cell growth in MIA PaCA-2, H358; effective in vivo. IC50: MIA-0.016μM, H358-0.028μM.Formula:C31H36ClFN6O2Colore e forma:SolidPeso molecolare:579.11(R)-ZG197
(R)-ZG197: Activates Sa ClpP (EC50=1.5μM) & Hs ClpP (EC50=31.4μM); selective for Sa ClpP.Formula:C28H35F3N4O3Colore e forma:SolidPeso molecolare:532.6Mal-PEG4-VA-PBD
CAS:Mal-PEG4-VA-PBD is a drug-linker conjugate for Antibody-Drug Conjugates (ADCs), comprising the antitumor antibiotic Pyrrolobenzodiazepine (PBD), connectedFormula:C68H79N9O17Purezza:98%Colore e forma:SolidPeso molecolare:1294.41Lisuride
CAS:Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.Formula:C20H26N4OColore e forma:SolidPeso molecolare:338.45ZLMT-12
ZLMT-12: tacrine derivative, inhibits CDK2/CDK9, weak on AChE/BuChE, anti-proliferative, low toxicity, blocks S/G2/M phase, induces apoptosis.Formula:C26H31ClN6OColore e forma:SolidPeso molecolare:479.02ACT-672125
CAS:ACT-672125: Potent CXCR3 blocker, may treat autoimmunity, safe with dose-dependent efficacy in lung inflammation.Formula:C25H25F3N10O2SColore e forma:SolidPeso molecolare:586.59Antibiotic MA 144M2
CAS:Antibiotic MA 144M2, an anthracycline glycoside, targets gram-positive bacteria and tumors, derived from Streptomyces and aclacinomycin A conversion.Formula:C42H55NO16Colore e forma:SolidPeso molecolare:829.88Enantiomer of Sofosbuvir
Inactive enantiomer of Sofosbuvir, used for chronic hepatitis C; lacks reported biological activity.Formula:C22H29FN3O9PPurezza:98%Colore e forma:SolidPeso molecolare:529.45CHK1-IN-4
CAS:CHK1-IN-4 is a potent inhibitor of checkpoint kinase 1 (chk1) and potently inhibits chk1 phosphorylation in the tumor cells with anti-tumor activity.Formula:C18H18BrN7O2Purezza:98%Colore e forma:SolidPeso molecolare:444.29Anticancer agent 28
Anticancer agent 28 is 50x more potent than Oridonin, IC50 of 0.09 μM against K562; effective in H22 mouse tumors.Formula:C28H33NO6Colore e forma:SolidPeso molecolare:479.56A4B17
A4B17 is an inhibitor of androgen receptor N-terminal with potential for androgen-responsive prostate cancer treatment.Formula:C14H7F4NSColore e forma:SolidPeso molecolare:297.27PD-1-IN-17
CAS:PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at 100 nM.Formula:C13H22N6O7Purezza:99.6%Colore e forma:SolidPeso molecolare:374.35Antibacterial agent 82
Antibacterial agent 82 (compound 7p) is an antibacterial agent [1].Formula:C22H18N2O2Colore e forma:SolidPeso molecolare:342.39NS2B/NS3-IN-4
CAS:Compound 34e inhibits DENV2/ZIKV proteases; IC50: 0.69 µM (DENV2), 1.04 µM (ZIKV).Formula:C15H11NO4Colore e forma:SolidPeso molecolare:269.25Musettamycin
CAS:Musettamycin triggers erythroid differentiation in blood cells, acts like anthracycline antibiotics, but only inhibits gram-positive bacteria.Formula:C36H45NO14Colore e forma:SolidPeso molecolare:715.74BRD50837
CAS:BRD50837 is a potent and selective inhibitor of Sonic Hedgehog (Shh).Formula:C26H32ClN3O6SPurezza:98%Colore e forma:SolidPeso molecolare:550.07(rel)-Myrislignan
CAS:(rel)-Myrislignan, a lignan compound with a relative configuration, has been isolated from Myristica fragrans Houtt.Formula:C21H26O6Purezza:98%Colore e forma:SolidPeso molecolare:374.43HIV-1 inhibitor-14
HIV-1 inhibitor-14: potent, broad HIV-1 RT inhibitor. IC50=0.14μM. Effective against wild-type and resistant strains, EC50=5.79-28.3nM.Formula:C29H32N6O4SColore e forma:SolidPeso molecolare:560.67Cap-dependent endonuclease-IN-14
CAS:Cap-dependent endonuclease-IN-14 hinders CEN and could treat influenza virus infections. (Patent CN113620948A, compound 1-c).Formula:C30H23FN2O6SColore e forma:SolidPeso molecolare:558.58β-N-Acetyl-D-hexosaminidase-IN-1
β-N-Acetyl-D-hexosaminidase-IN-1 is a newly discovered chemical compound that acts as an inhibitor for β-N-acetyl-D-hexosaminidase.Formula:C18H13F2NO2SColore e forma:SolidPeso molecolare:345.36KH-259
KH-259: potent, selective CNS-penetrant HDAC6 inhibitor with 0.26 μM IC50; shows antidepressant effects in mice.Formula:C20H25N3O2Colore e forma:SolidPeso molecolare:339.43Antiangiogenic agent 3
Antiangiogenic agent 3 blocks HUVEC cell migration, chemotaxis, and lowers Src, cdc42, MAPK gene expression.Formula:C19H20O7Colore e forma:SolidPeso molecolare:360.36ABD957
CAS:ABD957: covalent ABHD17 depalmitoylases inhibitor, IC50 0.21µM for ABHD17B, blocks N-Ras, halts NRAS-mutant AML cell growth.Formula:C27H36F3N7O5SColore e forma:SolidPeso molecolare:627.68CRS-3123
CAS:CRS-3123, a methionyl-tRNA synthetase inhibitor, is used potentially for the treatment of enteric infections.Formula:C19H19Br2N3O2SPurezza:98%Colore e forma:SolidPeso molecolare:513.25K252d
CAS:K252d: indolocarbazole alkaloid in Nocardiopsis; inhibits PKC in rat brain and bovine heart phosphodiesterase.
Formula:C26H23N3O5Colore e forma:SolidPeso molecolare:457.484,5'-Dimethylangelicin-NHS
NHS-modified coumarin, 4,5'-Dimethylangelicin-NHS, shows photochemical activity & photosensitivity.Formula:C21H19NO7SColore e forma:SolidPeso molecolare:429.44LY3130481
CAS:LY3130481: TARP γ-8 dependent AMPA receptor blocker; selectively targets AMPA/TARP γ-8 with 65 nM IC50.Formula:C19H18N4O3SColore e forma:SolidPeso molecolare:382.44CB1/2 agonist 1
Potent CB1/2 agonist 1; crosses blood-brain barrier; anti-inflammatory, analgesic; for multiple sclerosis research.Formula:C21H24BrFN2O2Colore e forma:SolidPeso molecolare:435.33Indoluidin E
Indoluidin E selectively inhibits DHODH and has an inhibitory effect on cancer cell growth.Formula:C28H30N4O2Colore e forma:SolidPeso molecolare:454.56Triciferol
CAS:Triciferol is a VDR agonist and HDAC antagonist with 1,25D-like potency, affecting gene targets and tubulin, and shows anti-cancer effects in vitro. IC50=87nM.Formula:C26H39NO4Colore e forma:SolidPeso molecolare:429.591BAY-850 HCl
BAY-850 is a selective probe targeting Atad2A's bromine domain, displacing acetylated H4 peptides and detaching ATAD2 from chromatin at 1μm.Formula:C38H48Cl5N5O3Colore e forma:SolidPeso molecolare:800.08KU 59403
CAS:KU 59403 is an effective ATM inhibitor (IC50: 3 nM, 9.1 μM, and 10 μM for ATM, DNA-PK, and PI3K, respectively).Formula:C29H32N4O4S2Purezza:99.10%Colore e forma:SolidPeso molecolare:564.72Antiallergic agent-1
Antiallergic agent-1, an Src family kinase inhibitor, is a new and valuable lead compound with potential as an anti-allergic agent.Formula:C27H19F6N5OColore e forma:SolidPeso molecolare:543.46CS-0777
CAS:CS-0777 is a potent, selective, and orally active S1P1 agonist (sphingosine 1-phosphate receptor modulator).Formula:C21H31N2O5PColore e forma:SolidPeso molecolare:422.45BAY 38-7271
CAS:BAY 38-7271: potent neuroprotective, selective CB1/CB2 agonist, Ki of 1.85 nM (CB1) & 5.96 nM (CB2).Formula:C20H21F3O5SPurezza:98%Colore e forma:SolidPeso molecolare:430.44AY-22,252
CAS:AY-22,252 is an inhibitor of beef heart & rat brain nucleoside-3',5'- monophosphate phosphodiesterase.Formula:C27H37NaO7Colore e forma:SolidPeso molecolare:496.57CHK1 inhibitor
CAS:CHK1 inhibitor (GDC-0575 analog) is a CHK1 inhibitor.Formula:C17H21BrN4OPurezza:98%Colore e forma:SolidPeso molecolare:377.2816(R)-Iloprost
CAS:Iloprost, a potent prostacyclin analog, binds IP & EP1 receptors (Ki 11 nM), contains 16(S/R) isomers, and inhibits platelets (IC50 65 nM).Formula:C22H32O4Colore e forma:SolidPeso molecolare:360.49Diguanosine 5′-triphosphate lithium
Diguanosine 5′-triphosphate (Gp3G) lithium is a dinucleoside triphosphate and a virus-specific oligonucleotide.Diguanosine 5′-triphosphate lithium is requiredFormula:C20H27N10O18P3·xLiColore e forma:SolidFXIa-IN-9
CAS:FXIa-IN-9, a potent FXIa inhibitor (K i : human 0.17 nM, rabbit 0.5 nM), forms hydrogen bonds and has anticoagulant properties.Formula:C23H18Cl2F3N9O2Colore e forma:SolidPeso molecolare:580.35HP590
CAS:HP590: potent oral STAT3 inhibitor, IC50=27.8 nM, blocks ATP, IC50=24.7 nM, hinders gastric cancer growth, triggers cell death.Formula:C29H24F6N4O3Colore e forma:SolidPeso molecolare:590.52EGFR-IN-45
EGFR-IN-45: Strong EGFR/CDK2 inhibitor (IC50s: 0.4 & 1.6 μM), halts cancer cell cycle pre-G1, prompts apoptosis, also targets Topo I/II.Formula:C28H23N7OColore e forma:SolidPeso molecolare:473.53KRAS G12C inhibitor 15
CAS:KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor .Formula:C25H21ClF2N4O3Purezza:98%Colore e forma:SolidPeso molecolare:498.91CBR Agonist-1
CBR Agonist-1 targets CB1R and CB2R with Ki of 0.18 μM and 1.22 μM, useful for studying cannabinoid-related diseases.Formula:C27H27FN4OColore e forma:SolidPeso molecolare:442.53PF-06726304 acetate
CAS:PF-06726304 acetate is a selective inhibitor of EZH2, with robust antitumor growth activity.Formula:C24H25Cl2N3O5Purezza:98%Colore e forma:SolidPeso molecolare:506.38
