Inibitori
Gli inibitori sono molecole che si legano a enzimi, recettori o altre proteine per ridurre o bloccare la loro attività biologica. Questi composti sono ampiamente utilizzati nella ricerca per studiare le vie biologiche, comprendere i meccanismi delle malattie e sviluppare farmaci terapeutici. Gli inibitori svolgono un ruolo cruciale nel trattamento di varie malattie, tra cui il cancro, le malattie cardiovascolari e le infezioni. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità per supportare le tue ricerche in biochimica, biologia cellulare e sviluppo farmaceutico.
Sottocategorie di "Inibitori"
- Angiogenesi(2.687 prodotti)
- Apoptosi(6.097 prodotti)
- Ciclo cellulare/Checkpoint(4.691 prodotti)
- Cromatina/Epigenetica(2.376 prodotti)
- Segnalazione citoscheletrica(1.472 prodotti)
- Danno al DNA/Riparazione del DNA(2.921 prodotti)
- Endocrinologia/Ormoni(3.611 prodotti)
- Enzima(3.655 prodotti)
- Proteina G/GPCR(8.755 prodotti)
- Immunologia e infiammazione(3.765 prodotti)
- Virus dell'influenza(298 prodotti)
- Segnalazione JAK/STAT(407 prodotti)
- Segnalazione MAPK(1.230 prodotti)
- Trasportatore di membrana/canale ionico(2.947 prodotti)
- Metabolismo(9.940 prodotti)
- Microbiologia/Virologia(7.347 prodotti)
- Neuroscienza(10.240 prodotti)
- Altri inibitori(36.533 prodotti)
- Ossidazione-riduzione(43 prodotti)
- Segnalazione PI3K/Akt/mTOR(1.437 prodotti)
- Proteasi/Proteasoma(1.675 prodotti)
- Cellule staminali e Derivati(830 prodotti)
- Adattatori Tirosin-chinasi(2.028 prodotti)
- Ubiquitinazione(1.682 prodotti)
Mostrare 16 più sottocategorie
Trovati 66582 prodotti di "Inibitori"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
OXS007417
OXS007417 induces AML cell differentiation at 48 nM EC50 and shows potent in vivo antitumor effects.Formula:C20H14F3N3OColore e forma:SolidPeso molecolare:369.34JAK3/BTK-IN-4
CAS:JAK3/BTK-IN-4, a dual inhibitor for JAK3/BTK, shows synergy in autoimmune disease treatment. (Patent WO2021147953A1, compound 003)Formula:C21H25ClN8OColore e forma:SolidPeso molecolare:440.93KRAS G12C inhibitor 56
CAS:KRAS G12C inhibitor 56, a powerful inhibitor of SOS1 with an inhibitory concentration (IC50) of 1.6 nM, holds promise for use in cancer research.Formula:C32H39N7O4SColore e forma:SolidPeso molecolare:617.76Anticancer agent 53
CAS:Anticancer agent 53 exhibits potent in vitro cytotoxicity, triggers apoptosis, halts S/G2/M cycle, and has antitumor effects without toxicity.Formula:C31H25FN4O6SColore e forma:SolidPeso molecolare:600.62Fonsartan free acid
CAS:Fonsartan: Angiotensin receptor blocker, halts angiotensin II effects on rat vascular cells.Formula:C26H32N4O5S2Purezza:98%Colore e forma:SolidPeso molecolare:544.69SARS-CoV-2-IN-22
CAS:<p>SARS-CoV-2-IN-22 is a SARS-CoV-2 pseudovirus inhibitor (IC50: 16.96 μM).</p>Formula:C27H24N2O3SColore e forma:SolidPeso molecolare:456.56PD-1/PD-L1-IN-13
PD-1/PD-L1-IN-13 is a potent immune checkpoint PD-1/PD-L1 inhibitor with an IC50 value of 10.2 nM for PD-1/PD- L1 interaction.PD-1/PD-L1-IN-13 promotes CD8+ T-Formula:C36H34ClF2N3O9Colore e forma:SolidPeso molecolare:726.12BTK-IN-6
BTK-IN-6, a potent BTK inhibitor, may treat immune, cardiac, cancer, viral, inflammatory, metabolic, and neurological disorders.Formula:C23H22FN5O3Colore e forma:SolidPeso molecolare:435.45CHK1 inhibitor
CAS:CHK1 inhibitor (GDC-0575 analog) is a CHK1 inhibitor.Formula:C17H21BrN4OPurezza:98%Colore e forma:SolidPeso molecolare:377.28hCA IX-IN-1
<p>hCA IX-IN-1 inhibits human carbonic anhydrases I, II, IX, and XII with Ki values of 331.4, 28.4, 9.4, 17.8 nM and exhibits anticancer properties.</p>Formula:C19H18N2O3SColore e forma:SolidPeso molecolare:354.42O4
CAS:<p>O4 is a novel stabilizer of amyloid- fibrils. O4 used for accelerating the formation of end-stage mature fibrils.</p>Formula:C24H15NO7Purezza:98%Colore e forma:SolidPeso molecolare:429.38Danshenxinkun D
CAS:Danshenxinkun D has antituberculosis H_(37)Rv activity in vitro.Formula:C21H20O4Purezza:98%Colore e forma:SolidPeso molecolare:336.38VEGFR-2-IN-17
VEGFR-2-IN-17 (15a) is a potent VEGFR-2 inhibitor with an IC50 of 67.25 nM, showing significant antitumor effects.Formula:C21H14ClN3O2Colore e forma:SolidPeso molecolare:375.81UK 356618
CAS:<p>UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM).</p>Formula:C34H43N3O4Purezza:98%Colore e forma:SolidPeso molecolare:557.72HIV-IN-3
<p>HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.</p>Formula:C21H32ClN7O3Colore e forma:SolidPeso molecolare:465.98iMDK quarterhydrate
iMDK quarterhydrate, PI3K inhibitor, blocks MDK growth; suppresses NSCLC safely with MEK inhibitor.Formula:C21H15FN2O3SColore e forma:SolidPeso molecolare:380.91Turoctocog alfa
CAS:Turoctocog alfa: recombinant FVIII from CHO cells for hemophilia A study.Colore e forma:SolidKPC-2-IN-2
KPC-2-IN-2 (6c) inhibits KPC-2 enzyme in Klebsiella pneumoniae (Ki 0.038 μM) and boosts cefotaxime in E. coli KPC-2.Formula:C12H10BN3O2SColore e forma:SolidPeso molecolare:271.1AZ12971554
AZ12971554: Human thrombin inhibitor, Ki=0.3nM; APTT IC50=0.68µM; ECT IC50=0.16µM.Formula:C20H17ClFN7O3Colore e forma:SolidPeso molecolare:457.85Leustroducsin B
CAS:Leustroducsin B is a novel colony-stimulating factor (CSF) inducer extracted from Streptomyces platensis SANK 60191.Formula:C34H56NO10PColore e forma:SolidPeso molecolare:669.78CYP2C9/CYP2C19-IN-1
CYP2C9/CYP2C19-IN-1 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection.Formula:C27H28N2O6SColore e forma:SolidPeso molecolare:508.59MAP855
CAS:MAP855: potent, selective, oral MEK1/2 inhibitor; IC50=3 nM, pERKEC50=5 nM; effective on wild-type/mutant MEK1/2.Formula:C28H23ClF2N6O3Colore e forma:SolidPeso molecolare:564.97P053
CAS:<p>P053: potent, selective CerS1 inhibitor, IC50 = 0.5µM, curbs muscle fat oxidation, affects body fat.</p>Formula:C18H21Cl2NO2Purezza:98%Colore e forma:SolidPeso molecolare:354.27Saussureamine C
CAS:Saussureamine C is an inhibitor of H274Y and N294S mutants.Formula:C19H26N2O5Colore e forma:SolidPeso molecolare:362.42MRS4458
CAS:<p>MRS4458 is an effective inhibitor of the P2Y14 Receptor.</p>Formula:C24H20F3N5O3SPurezza:98%Colore e forma:SolidPeso molecolare:515.51Mevidalen HBA
CAS:<p>Mevidalen (LY3154207), a potent D1 positive allosteric modulator, is in clinical trials for Lewy body dementia.</p>Formula:C31H35Cl2NO6Colore e forma:SolidPeso molecolare:588.52G-479
CAS:<p>G-479, a potent MEK inhibitor and improved analogue of GDC-0623, has distributed polarity enhancing bioactivity.</p>Formula:C16H15FIN5O4Colore e forma:SolidPeso molecolare:487.22SH498
CAS:<p>SH498 is a novel Bmi-1-mediated anti-tumor agent with significant anti-proliferative effects.</p>Formula:C27H25F3N2O4Colore e forma:SolidPeso molecolare:498.49Ambuic acid
CAS:Ambuic acid: cyclohexanone with antifungal, quorum-inhibiting, antibacterial properties, blocks cyclic peptides; reduces MRSA abscesses in mice.Formula:C19H26O6Colore e forma:SolidPeso molecolare:350.41Bcl-2-IN-8
Bcl-2-IN-8: potent, hinders cell growth/migration, induces apoptosis, promising in triple-negative breast cancer research.Formula:C36H44O6Colore e forma:SolidPeso molecolare:572.73HDAC-IN-35
HDAC-IN-35 (Compound 14) is an effective and selective inhibitor of VEGFR-2 and HDAC, with IC50 values of 13.2 and 0.166 μM for VEGFR-2 and HDAC6, respectively.Formula:C17H13ClF3N3O3Colore e forma:SolidPeso molecolare:399.75Anticancer agent 54
Anticancer agent 54 blocks cell cycle in G0/G1, induces apoptosis, and fights cancer via DNA embedding and ROS.Formula:C33H36N6Colore e forma:SolidPeso molecolare:516.68DC1SMe
CAS:<p>DC1, a CC-1065-like ADC cytotoxin, is used in cancer-targeting antibody-drug conjugates. DC1Sme, a derivative, has IC50s: 22-250 pm in various cancer cells.</p>Formula:C35H30ClN5O4S2Purezza:98%Colore e forma:SolidPeso molecolare:684.23PF-5177624
CAS:PF-5177624 is a selective and potent PDK1 inhibitor inducing anti-tumor activity in breast cancer cells.Formula:C25H25FN8O2Colore e forma:SolidPeso molecolare:488.52TRK-IN-12
CAS:TRK-IN-12 (9e), a macrocyclic TRK inhibitor (G595R IC50=13.1 nM), outperforms LOXO-101 in Ba/F3-NTRK1 cells.Formula:C18H19ClFN5O3SColore e forma:SolidPeso molecolare:439.89Xeruborbactam
CAS:QPX7728 is an of ultra-broad-spectrum boronic acid beta-lactamase.Formula:C10H8BFO4Purezza:98%Colore e forma:SolidPeso molecolare:221.98T-3764518
CAS:T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).Formula:C20H17F6N5O2Purezza:98%Colore e forma:SolidPeso molecolare:473.37GDC-0339
CAS:GDC-0339: oral Pim kinase inhibitor for multiple myeloma (Kis: Pim1 - 0.03 nM, Pim2 - 0.1 nM, Pim3 - 0.02 nM), well-tolerated.Formula:C20H22F3N7OSColore e forma:SolidPeso molecolare:465.5FTI-2628
CAS:FTI-2628 is a novel inhibitor of protein farnesyltransferase (FT), inhibiting the growth of P. falciparum in red blood cells and suppressing parasitemia.Formula:C31H34N4O3SColore e forma:SolidPeso molecolare:542.69hMAO-B/MB-COMT-IN-2
Dual inhibitor hMAO-B/MB-COMT-IN-2 targets hMAO-B (IC50: 4.27μM) & MB-COMT (IC50: 2.69μM), aids in neurodegenerative research.Formula:C17H18N2O3Colore e forma:SolidPeso molecolare:298.34Anticancer agent 27
Anticancer agent 27 is a promising candidate for the treatment of cancer and deserves further development.Formula:C28H31NO6Colore e forma:SolidPeso molecolare:477.55COX-2-IN-13
COX-2-IN-13 is a potent, selective COX-2 inhibitor with 0.98 μM IC50; shows strong anti-inflammatory properties and low acute toxicity.Formula:C19H18N2O5SColore e forma:SolidPeso molecolare:386.42DYRK1-IN-1
CAS:<p>DYRK1-IN-1: Selective DYRK1A inhibitor with IC50 of 220 nM, good permeability, CNS penetrant for research, no P-glycoprotein issues.</p>Formula:C12H12N6Colore e forma:SolidPeso molecolare:240.26AN-12-H5
CAS:AN-12-H5 is an anti-enteroviral compound that targets the replication process of PV and EV71 viruses.Formula:C24H23N3O4S3Colore e forma:SolidPeso molecolare:513.65COX-2-IN-7
<p>COX-2-IN-7: potent, orally active COX-2 inhibitor with higher selectivity than Celecoxib, IC50 6.585 uM, anti-inflammatory, low ulcer risk.</p>Formula:C15H13N3O2S2Colore e forma:SolidPeso molecolare:331.41Chk1-IN-5
CAS:Chk1-IN-5 inhibits Chk1, blocking phosphorylation and suppressing colon cancer growth.Formula:C18H18FN7O2Colore e forma:SolidPeso molecolare:383.38GSK789
CAS:<p>GSK789 is a selective inhibitor of the first bromodomains (BD1) of the bromo and extra terminal domain (BET) proteins.</p>Formula:C26H33N5O3Colore e forma:SolidPeso molecolare:463.57ZIKV-IN-5
ZIKV-IN-5 is an acid-stable, low cytotoxic anti-ZIKV agent with an EC50 value of 0.71 μM. ZIKV-IN-5 showed effective inhibition of ZIKV NS5 MTase activity.Formula:C36H45NO4SiColore e forma:SolidPeso molecolare:583.83Antitumor agent-75
Antitumor agent-75 is a novel and potent antitumor agent.Formula:C26H23FN6Colore e forma:SolidPeso molecolare:438.5L-Sepiapterin
CAS:L-Sepiapterin aids in making BH4, a coenzyme essential for eNOS, enhancing artery function and angiogenesis, while suppressing ovarian cancer cell growth.Formula:C9H11N5O3Colore e forma:SolidPeso molecolare:237.22Bulgecin A
CAS:Bulgecin A is an inhibitor of binuclear metallo-beta-lactamases and Lytic transglycosolase.Formula:C16H29N3O14S2Colore e forma:SolidPeso molecolare:551.54ATM Inhibitor-1
CAS:<p>ATM Inhibitor-1 is a highly potent, selective and orally active ATM inhibito (IC50: 0.7 nM) anti-tumor activity.</p>Formula:C27H36N6O3Purezza:98%Colore e forma:SolidPeso molecolare:492.61Streptothricin F
CAS:<p>Streptothricin F is a biochemical.</p>Formula:C19H34N8O8Colore e forma:SolidPeso molecolare:502.52VEGFR-2-IN-26
CAS:VEGFR-2-IN-26 inhibits VEGFR-2 (IC50: 15.5 nM), combating various cancers' cell growth.Formula:C24H19F3N6O2Colore e forma:SolidPeso molecolare:480.44DNA-PK-IN-9
DNA-PK-IN-9 (YK6) is a potent DNA-PK inhibitor with an IC50 of 10.47 nM, important in cancer research.Formula:C21H21N5O2Colore e forma:SolidPeso molecolare:375.42LP 12 hydrochloride hydrate
LP 12 hydrochloride hydrate: potent, selective 5-HT7 agonist (Ki: 0.13 nM); less affinity for D2, 5-HT1A/2A receptors.Formula:C32H39N3O·HCl·xH2OColore e forma:SolidAntifungal agent 17
Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).Formula:C18H16Br2O2Colore e forma:SolidPeso molecolare:424.13Thalicarpine
CAS:<p>Thalicarpine, a natural anticancer alkaloid, inhibits p-glycoprotein and induces DNA damage, arresting cell cycle.</p>Formula:C41H48N2O8Colore e forma:SolidPeso molecolare:696.83Pexacerfont
CAS:Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor).Formula:C18H24N6OPurezza:99.77%Colore e forma:SolidPeso molecolare:340.42AK-295
CAS:<p>AK 295, also known as CX 295, is a dipeptide inhibitor of alpha-ketoamide calpain.</p>Formula:C26H40N4O6Colore e forma:SolidPeso molecolare:504.62BAY-179
CAS:BAY-179 is a potent, selective, species cross-reactive complex I inhibitor for the study of cancer.Formula:C23H21N5OSPurezza:98.29%Colore e forma:SolidPeso molecolare:415.51rel-MDM2/4-p53-IN-2
Potent dual MDM2/MDM4 inhibitor & p53 activator; IC50: 70.7 nM (MDM2), 81.4 nM (MDM4); regulates cell cycle, triggers apoptosis, anti-cancer.Formula:C25H17Cl3FN3O3Colore e forma:SolidPeso molecolare:532.78ORIC-101
CAS:ORIC-101 is a highly effective and selective glucocorticoid receptor antagonist (EC50: 5.6 nM). It also has anti-cancer activity.Formula:C34H47NO2Purezza:98%Colore e forma:SolidPeso molecolare:501.74PF-06648671
CAS:<p>PF-06648671 is a γ-secretase modulator for the treatment of neurodegenerative and/or neurological disorders.</p>Formula:C25H23ClF4N4O3Purezza:98%Colore e forma:SolidPeso molecolare:538.92NR1H4 activator 1
CAS:NR1H4 activator 1 is a potent and selective agonist of Famesoid X Receptor (FXR).Formula:C34H53NO7SPurezza:98%Colore e forma:SolidPeso molecolare:619.85NSD2-IN-1
CAS:<p>NSD2-IN-1: potent, selective NSD2-PWWP1 inhibitor, IC50 0.11 μM, induces gene expression changes, apoptosis, cell cycle arrest.</p>Formula:C29H31N5Colore e forma:SolidPeso molecolare:449.59SJG-136
CAS:SJG-136 is a DNA cross-linking agent (XL50: 45 nM for pBR322 DNA).Formula:C31H32N4O6Purezza:98%Colore e forma:SolidPeso molecolare:556.61hAChE/Aβ1-42-IN-1
CAS:Compound 16 (hAChE/Aβ1-42-IN-1) is a potent inhibitor targeting both hAChE and Aβ1-42 aggregation, demonstrating considerable safety in hepG2 cell lines andFormula:C20H24N6OColore e forma:SolidPeso molecolare:364.44Taranabant
CAS:<p>Taranabant: potent CB1 receptor inverse agonist; inhibits agonists with 0.13 nM Ki in vitro.</p>Formula:C27H25ClF3N3O2Purezza:99.06% - 99.06%Colore e forma:SolidPeso molecolare:515.96NF-κB-IN-4
NF-κB-IN-4 (compound 17) is a potent inhibitor of NF-κB pathway which can cross blood brain barrier (BBB).Formula:C18H15FN4OColore e forma:SolidPeso molecolare:322.34AZD-4121 tert-butylammonium
CAS:AZD-4121 tert-butylammonium is an oral cholesterol absorption inhibitor targeting NPC1L1 for the treatment of dyslipidaemia.Formula:C40H50F2N4O7SColore e forma:SolidPeso molecolare:768.91Lipoxin A5
CAS:LXA5 is made from EPA by leukocytes, contracts guinea pig lungs like LXA4/LXB4, but doesn't dilate aorta.Formula:C20H30O5Colore e forma:SolidPeso molecolare:350.45Homopteroic Acid
CAS:Homopteroic Acid, a precursor to Homofolic Acid, inhibits L1210 mouse leukemia growth by targeting folate uptake.Formula:C15H14N6O3Colore e forma:SolidPeso molecolare:326.31Antibiotic MA 144M1
CAS:Antibiotic MA 144M1, an anthracycline, targets gram-positive bacteria and animal tumors; derived from Streptomyces fermentation or aclacinomycin A conversion.Formula:C42H55NO15Colore e forma:SolidPeso molecolare:813.88SLC4011540
SLC4011540 is a potent and selective SphK1/2 dual inhibitor with Ki value of 120 nM and 90 nM respectively.Formula:C24H23ClF3N7OSColore e forma:SolidPeso molecolare:550Tasidotin hydrochloride
CAS:Tasidotin hydrochloride, a dolastatin 15 analog, inhibits microtubule assembly and dynamics.Formula:C32H59ClN6O5Purezza:98%Colore e forma:SolidPeso molecolare:643.30HDAC6-IN-9
CAS:HDAC6-IN-9 is a γ-secretase modulator that can significantly reduce the level of Aβ42 in mouse brain and can be used to study neurological diseases.Formula:C19H16N2O3Purezza:98.84%Colore e forma:SolidPeso molecolare:320.34IDO1-IN-13
<p>IDO1-IN-13 is a potent IDO1 inhibitor (IC50: 61.6 nM, EC50: 30 nM in HeLa) that reduces kyn/trp ratio by 51% in SK-OV-3 tumors.</p>Formula:C20H16BrN5O2SColore e forma:SolidPeso molecolare:470.34(-)-Adenophorine
CAS:(-)-Adenophorine is a moderate alpha-l-fucosidase inhibitor.Formula:C8H17NO4Colore e forma:SolidPeso molecolare:191.22MK-7128
CAS:<p>MK-7128 is a CB1 receptor inverse agonist.</p>Formula:C29H25ClF2N4O2Colore e forma:SolidPeso molecolare:534.98Anticancer agent 16
<p>Anticancer agent 16 showed good cytotoxic effects on HCT-116 cell line (IC50: 8.55 μM), NCI-H460 cell line (IC50: 5.41 μM) and SKOV3 cell line (IC50: 6.4 μM).</p>Formula:C27H33N5O6Colore e forma:SolidPeso molecolare:523.58Calphostin A
CAS:Calphostins, from Cladosporium fungus, inhibit PKC; calphostin C is most potent, used as a biochemical tool.Formula:C44H38O12Colore e forma:SolidPeso molecolare:758.77AFP-07
CAS:<p>AFP-07 is a highly selective and potent agonist. It was used for the prostacyclin receptor.</p>Formula:C22H29F2NaO5Purezza:98%Colore e forma:SolidPeso molecolare:434.45Ataprost
CAS:Ataprost (ONO 41483), an oral Carboprostacyclin analogue, is 2.6x more potent in inhibiting ADP-induced platelet aggregation and can relieve coronary spasm.Formula:C21H32O4Colore e forma:SolidPeso molecolare:348.48NMDAR/HDAC-IN-1
<p>Compound 9d is a dual NMDAR and HDAC inhibitor with high NMDAR affinity (Ki=0.59 μM) and inhibits HDAC1-3,6,8; crosses the blood-brain barrier.</p>Formula:C22H28N2O3Colore e forma:SolidPeso molecolare:368.47Odiparcil
CAS:Odiparcil is an orally active beta-d-thioxyloside analog.Formula:C15H16O6SPurezza:98%Colore e forma:SolidPeso molecolare:324.35Cdc7-IN-11
CAS:Cdc7-IN-11 is a potent inhibitor of Cdc7 (IC50 ≤ 1 nM) and can be used in the study of proliferative diseases.Formula:C20H22F2N4O2SColore e forma:SolidPeso molecolare:420.48GSK-2878175
CAS:GSK-2878175, a NS5B inhibitor, is used potentially for the treatment of HCV infection.Formula:C27H23BClFN2O6SPurezza:98%Colore e forma:SolidPeso molecolare:568.81CDK1-IN-5
CDK1-IN-5 is a selective inhibitor for CDK1 (IC50: 42.19 nM), CDK2, CDK5, halting cancer cell growth.Formula:C27H26ClN5OSColore e forma:SolidPeso molecolare:504.05Colistin adjuvant-1
Colistin adjuvant-1, inhibits NF-κB (IC50: 0.209 μM), boosts mucin against gram-negative bacteria.Formula:C16H7F9N2OColore e forma:SolidPeso molecolare:414.23Nrf2 activator-6
CAS:Nrf2 activator-6, a tetrahydroisoquinoline, inhibits Kelch-Nrf2 at 5 nM IC50 (WO2021214470A1).Formula:C31H37ClFN5O5Colore e forma:SolidPeso molecolare:614.11AMXI-5001 hydrochloride
<p>AMXI-5001 hydrochloride, an oral inhibitor of PARP1/2 and microtubules, shows greater potency and selective anti-cancer effects.</p>Formula:C25H21ClFN5O3Colore e forma:SolidPeso molecolare:493.92RAD51-IN-6
CAS:RAD51-IN-6, a potent RAD51 gene inhibitor, may help research mitochondrial disorders. (WO2021164746A1, cmpd 23)Formula:C27H40N3O5PSColore e forma:SolidPeso molecolare:549.66AM8936
AM8936: potent CB1 agonist, EC50 rCB1=8.6nM/hCB1=1.4nM, Ki rat CB1=0.55nM; potential for CNS, metabolic, pain, glaucoma research.Formula:C25H33NO3Colore e forma:SolidPeso molecolare:395.53CAII-IN-3
CAII-IN-3, a thiosemicarbazone, potently inhibits CA-II with an IC50 of 13.4 μM.Formula:C18H18F2N4SColore e forma:SolidPeso molecolare:360.42WEHI-539
CAS:WEHI-539 is a selective Bcl-XL inhibitor (IC50: 1.1 nM).Formula:C31H29N5O3S2Purezza:98%Colore e forma:SolidPeso molecolare:583.72Encephalitic alphavirus-IN-1
Alphavirus-IN-1 blocks VEEV (EC50: 0.24 μM) & EEEV (EC50: 0.16 μM), non-toxic, stable in mice plasma.Formula:C27H25FN6O2Colore e forma:SolidPeso molecolare:484.52S100A2-p53-IN-1
CAS:<p>S100A2-p53-IN-1 inhibits S100A2-p53 in pancreatic cancer, stunting MiaPaCa-2 cell growth at 1.2-3.4 μM.</p>Formula:C20H20F6N2O4SColore e forma:SolidPeso molecolare:498.44TP-030-2
CAS:<p>TP-030-2 is a RIPK1 inhibitor (human K i =0.43 nM ; mouse IC 50 =100 nM) .</p>Formula:C23H21BrN4O3Colore e forma:SolidPeso molecolare:481.34FCE-27262
CAS:FCE-27262 is a prostaglandin H2/thromboxane A2 receptor antagonist.Formula:C23H31N3O3Colore e forma:SolidPeso molecolare:397.51Dot1L-IN-1
CAS:The Ki value of DOT1L-in-1 is 2pm.It is a highly effective, selective and novel Dot1L inhibitor.Formula:C32H36ClN9O2SPurezza:98%Colore e forma:SolidPeso molecolare:646.21UK-432097
CAS:UK 432097 is an adenosine A2A agonist.Formula:C40H47N11O6Colore e forma:SolidPeso molecolare:777.87Antitubulin agent 1
Antitubulin agents-1 disrupts microtubules, ups α-tubulin acetylation, and has anticancer properties.Formula:C21H19N3O3Colore e forma:SolidPeso molecolare:361.39BAY-364
CAS:BAY-364 (BAY-299N) functions as an inhibitor targeting the second bromine domain in TAF1, demonstrating inhibitory effects on TAF1 in Kasumi-1 cells, CD34+Formula:C23H19N3O4Colore e forma:SolidPeso molecolare:401.41p38 MAPK-IN-3
<p>Compound 2c is a potent p38α MAPK inhibitor with antitumor effects, enhancing apoptosis and ROS.</p>Formula:C22H17BrO2Colore e forma:SolidPeso molecolare:393.27KCL-440
CAS:RS 57639 is a bioactive chemical.Formula:C18H18N2O2Colore e forma:SolidPeso molecolare:294.35Iralukast (CGP 45715A)
CAS:Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1.Formula:C38H37F3O8SColore e forma:SolidPeso molecolare:710.76MS8511
CAS:<p>MS8511: Selective, irreversible G9a/GLP inhibitor. IC50: 100 nM (G9a), 140 nM (GLP). Lowers H3K9me2, anti-proliferative. Useful in cancer/AD/PWS research.</p>Formula:C28H41N5O3Colore e forma:SolidPeso molecolare:495.66Homomoschatoline
CAS:Homomoschatoline is an antibacterial isolated from Artabotrys crassifolius.Formula:C19H15NO4Purezza:98%Colore e forma:SolidPeso molecolare:321.33SK&F 108361
CAS:SK&F 108361 is a symmetric diol that binds HIV-1 protease symmetrically.Formula:C24H48N6O6Colore e forma:SolidPeso molecolare:516.67LASSBio-1632
LASSBio-1632: Novel anti-asthmatic, blocks PDE4A/D, reduces AHR & lung TNF-α, crosses BBB.Formula:C18H20N2O6SColore e forma:SolidPeso molecolare:392.43BM635 hydrochloride (1493762-74-5 free base)
BM635 hydrochloride is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).Formula:C25H30ClFN2OPurezza:98%Colore e forma:SolidPeso molecolare:428.97c-Met/HDAC-IN-2
CAS:Potent dual c-Met/HDAC inhibitor, IC50: HDAC1 5.4 nM, c-Met 18.49 nM; anti-cancer, induces apoptosis, G2/M arrest in HCT-116.Formula:C34H33N5O7Colore e forma:SolidPeso molecolare:623.66Nepaprazole sodium
CAS:Nepaprazole Na (TY-11345), a proton pump inhibitor, may treat gastric ulcers; it reduces H+/K(+)-ATPase activity, with IC50 of 5.8-9.9 microM.Formula:C18H18N3NaO2SColore e forma:SolidPeso molecolare:363.41LY367385 hydrochloride
CAS:<p>LY367385 hydrochloride: selective mGluR1a antagonist, IC50 = 8.8 μM, neuroprotective, anticonvulsant, antiepileptic.</p>Formula:C10H12ClNO4Colore e forma:SolidPeso molecolare:245.66ZD6021
CAS:ZD6021 is an antagonist of neurokinin 1 receptor.Formula:C35H35Cl2N3O2SPurezza:98%Colore e forma:SolidPeso molecolare:632.64DS01080522
DS01080522: PRKACA inhibitor, IC50: kinase 0.8 nM, CREB 66 nM; potential for cancer research.Formula:C23H20Cl2N4O3Colore e forma:SolidPeso molecolare:471.34MDL-43291
CAS:MDL-43291 is a leukotriene receptor antagonist.Formula:C25H42O4SColore e forma:SolidPeso molecolare:438.66TIM-3-IN-1
TIM-3-IN-1 is a useful tool to enable further studies on the biology of TIM-3 immunoregulation in cancer.Formula:C20H16ClN7O3SColore e forma:SolidPeso molecolare:469.9PD-1-IN-17
CAS:<p>PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at 100 nM.</p>Formula:C13H22N6O7Purezza:99.6%Colore e forma:SolidPeso molecolare:374.35DMGF
CAS:DMGF, a biflavonoid from Taxus, induces apoptosis, autophagy, and inhibits B16F10 cell motility and MMP-2 expression, hindering melanoma metastasis.Formula:C32H22O10Colore e forma:SolidPeso molecolare:566.51IDH1 Inhibitor 1
CAS:Oral, brain-penetrant mutant IDH1 inhibitor targeting R132H/C with IC50: 0.021/0.045μM; 2.52μM for IDH1WT.Formula:C20H18F4N6O2Purezza:98%Colore e forma:SolidPeso molecolare:450.39DNDI-8219
CAS:DNDI-8219 is an antitubercular agent. It has potent antileishmanial effects.Formula:C13H10F3N3O5Colore e forma:SolidPeso molecolare:345.23C-di-IMP
CAS:Cyclic-di-IMP (C-di-IMP), a STING agonist, serves as a research tool in tumor studies.Formula:C20H22N8O14P2Colore e forma:SolidPeso molecolare:660.38Antifungal agent 13
CAS:Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.Formula:C21H16ClF3N4OColore e forma:SolidPeso molecolare:432.83Antiangiogenic agent 2
<p>Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase (IC50: 39.71 μM) and exhibits anti-angiogenic effects.</p>Formula:C26H26FN3O4Colore e forma:SolidPeso molecolare:463.5JBJ-02-112-05
CAS:JBJ-02-112-05 is a potent, mutant-selective, allosteric and orally active inhibitor of EGFR with an IC 50 of 15 nM for EGFR L858R/T790M [1].Formula:C27H20N4O2SPurezza:98%Colore e forma:SolidPeso molecolare:464.54Monoamine oxidase/Aromatase-IN-1
Compound 2q: Dual MAO/aromatase inhibitor; IC50: 39 nM (MAO-B), 31 nM (aromatase). Useful in neurological/breast cancer research.Formula:C19H19N3O3SColore e forma:SolidPeso molecolare:369.44EGFR/HER2/DHFR-IN-1
Potent EGFR/HER2/DHFR inhibitor for MCF-7 breast cancer; IC50: 0.153/0.108/0.291 μM; arrests G1/S phase, triggers apoptosis.Formula:C14H11BrN4O2SColore e forma:SolidPeso molecolare:379.23Gln-AMS TFA
Gln-AMS (TFA) is a type Ia amido-tRNA synthetase (AARS) inhibitor with a Ki value of 1.32 μM for glutaminyl-tRNA synthetase.Formula:C17H23F3N8O10SColore e forma:SolidPeso molecolare:588.47MrgprX2 antagonist-7
MrgprX2 antagonist-7 is an anti-allergic agent with significant anti-allergic effects and inhibits mast cell degranulation.Formula:C24H22ClF3N6O3Colore e forma:SolidPeso molecolare:534.92DMP 728
CAS:<p>DMP 728 is an antagonist of Glycoprotein IIb-IIIa.</p>Formula:C26H40N8O10SPurezza:98%Colore e forma:SolidPeso molecolare:656.71Dyrk1A-IN-4
CAS:Dyrk1A-IN-4, compound 48, is an oral DYRK1A/DYRK2 inhibitor with IC50s: 2 nM (DYRK1A), 6 nM (DYRK2), anticancer properties.Formula:C14H13F3N6Colore e forma:SolidPeso molecolare:322.29HDAC6/HSP90-IN-2
<p>HDAC6/HSP90-IN-2, a cancer research chemical, inhibits HDAC6 & Hsp90 with IC50s of 105.7 & 61 nM.</p>Formula:C19H22N2O5Colore e forma:SolidPeso molecolare:358.39XR8-69
<p>XR8-69 is a SARS-CoV-2 PLpro inhibitor. XR8-69 has a low micromolar antiviral effect in SARS-CoV-2 infected human cells.</p>Formula:C26H30N4O2SColore e forma:SolidPeso molecolare:462.61Kallikrein-IN-1
CAS:Kallikrein-IN-1 (Formula A) is an inhibitor of the kinin-releasing enzyme Kallikrein.Formula:C28H26FN5O4Colore e forma:SolidPeso molecolare:515.54Azaphilone-9
CAS:<p>AZA-9 inhibits cancer growth by blocking HuR-ARE RNA binding; IC50=1.2μM.</p>Formula:C21H23BrO5Colore e forma:SolidPeso molecolare:435.31Soyacerebroside II
CAS:Soyacerebroside II is a Ca2+ ionophore; both I and II inhibit IL-18 in PBMCs and modulate immune responses.Formula:C40H75NO9Purezza:98%Colore e forma:SolidPeso molecolare:714.02Enantiomer of Sofosbuvir
Inactive enantiomer of Sofosbuvir, used for chronic hepatitis C; lacks reported biological activity.Formula:C22H29FN3O9PPurezza:98%Colore e forma:SolidPeso molecolare:529.45NCI-006
CAS:<p>NCI-006, an LDH inhibitor, slows tumor growth and enhances pyruvate's role in mitochondrial metabolism.</p>Formula:C31H24F2N4O4S3Colore e forma:SolidPeso molecolare:650.74α-Glucosidase-IN-17
CAS:α-Glucosidase-IN-17 (Compound 12B) is a potent and orally active inhibitor of α-glucosidase, demonstrating antidiabetic activity with an inhibitoryFormula:C30H27NO2SColore e forma:SolidPeso molecolare:465.61CRV431
CAS:CRV431 is a novel Pan-Cyclophilin Inhibitor, potently inhibiting all cyclophilin isoforms tested - A, B, D, and G (IC50 values ranged from 1-7 nM).Formula:C67H122N12O13Colore e forma:SolidPeso molecolare:1303.76PI3K-IN-29
CAS:<p>PI3K-IN-29: Strong PI3K block, inhibits Akt phosphorylation. IC50: U87MG 0.264µM, HeLa 2.04µM, HL60 1.14µM.</p>Formula:C27H22ClN7O3SColore e forma:SolidPeso molecolare:560.03KR-67607
CAS:KR-67607, or NTX-101, is a novel 11β-HSD1 inhibitor that protects against eye injury by reducing cortisol and preserving eye structures.Formula:C24H29Cl2F3N4O4SColore e forma:SolidPeso molecolare:597.48(Z)-Lanoconazole
<p>(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.</p>Formula:C14H10ClN3S2Colore e forma:SolidPeso molecolare:319.832R,4R-Sacubitril
CAS:2R,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is used in combination with valsartan for the treatment of patients with heart failure.Formula:C24H29NO5Purezza:98%Colore e forma:SolidPeso molecolare:411.49Aurora inhibitor 1
CAS:<p>Aurora inhibitor 1 is a potent Aurora inhibitor (IC50: ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase).</p>Formula:C23H25N9SPurezza:98%Colore e forma:SolidPeso molecolare:459.57SPR7
SPR7 is a potent and selective rhodesain inhibitor (Ki: 0.51 nM). SPR7 exhibited antiparasitic effects against T. b. brucei (EC50: 1.65 μM).Formula:C30H32ClN3O3Colore e forma:SolidPeso molecolare:518.05Furametpyr
CAS:Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.Formula:C17H20ClN3O2Purezza:98%Colore e forma:SolidPeso molecolare:333.81Cimpuciclib tosylate
CAS:Cimpuciclib tosylate, a selective CDK4 inhibitor (IC50: 0.49 nM), exhibits anti-tumor activity.Formula:C37H43FN8O4SColore e forma:SolidPeso molecolare:714.85Aβ42-IN-1
CAS:Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM).Formula:C29H27ClN4O2Purezza:98%Colore e forma:SolidPeso molecolare:499SCH-1473759
CAS:SCH-1473759 is an inhibitor of the aurora (IC50s: 4 and 13 nM for Aurora A and B, respectively).Formula:C20H26N8OSPurezza:98%Colore e forma:SolidPeso molecolare:426.54RmlA-IN-2
RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).Formula:C22H26BrN5O4SColore e forma:SolidPeso molecolare:536.44MV061194
CAS:MV061194 is a potent and selective cathepsin K (Cat K) inhibitor.Formula:C28H37N5O4SColore e forma:SolidPeso molecolare:539.69PF-00446687
CAS:PF-00446687 is a selective agonist of melanocortin-4 receptor (MC4R) (EC50 of 12 ± 1 nM).Formula:C28H36F2N2O2Purezza:98%Colore e forma:SolidPeso molecolare:470.59TNP-470
CAS:<p>TNP-470 is a methionine aminopeptidase-2 inhibitor. TNP-470 is also an angiogenesis inhibitor.</p>Formula:C19H28ClNO6Purezza:98%Colore e forma:SolidPeso molecolare:401.88BSc5367
CAS:<p>BSc5367 inhibits Nek1 kinase (IC50: 11.5 nM), key in cell cycle, DNA repair, impacting ALS, PKD, cancer.</p>Formula:C20H15N3O2Colore e forma:SoildPeso molecolare:329.35Mibefradil
CAS:<p>Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s: 2.7 μM and 18.6 μM for T-type and L-type currents).</p>Formula:C29H38FN3O3Purezza:98%Colore e forma:SolidPeso molecolare:495.63Pateamine A
CAS:Pateamine A: marine-sourced macrolide from Mycale hentscheli; anticancer, antiviral, and translation inhibitor.Formula:C31H45N3O4SColore e forma:SolidPeso molecolare:555.77hCAII-IN-3
<p>hCAII-IN-3 inhibits key hCA isoforms with Ki: hCA I (403.8 nM), hCA II (5.1 nM), hCA IX (10.2 nM), hCA XII (5.2 nM); shows anticancer potential.</p>Formula:C17H21N3O3SColore e forma:SolidPeso molecolare:347.43p38-α MAPK-IN-5
CAS:p38-α MAPK-IN-5: potent p38α inhibitor, IC50s: 0.1 nM (α), 0.2 nM (β), 944 nM (γ), 4100 nM (δ); anti-inflammatory, promising for asthma/COPD research.Formula:C37H49N11O2Colore e forma:SolidPeso molecolare:679.86NNC-11-1585
CAS:NNC-11-1585 is an M(1) and M(2) muscarinic acetylcholine receptor (mAChR) agonist.Formula:C18H19N3OSColore e forma:SolidPeso molecolare:325.43cis-4-Br-2,5-F2-PCPA
<p>cis-4-Br-2,5-F2-PCPA (S1024) blocks LSD1/LSD2 (Ki: 94 nM/8.4 μM), hinders cancer stem cell growth, raises H3K4me2 in CCRF-CEM cells.</p>Formula:C9H8BrF2NColore e forma:SolidPeso molecolare:248.07DSP-1053 benzenesulfonate
CAS:DSP-1053: Benzylpiperidine-based, potent SERT inhibitor (Ki=1.02nM), partial 5-HT1A receptor agonist (Ki=5.05nM), antidepressant.Formula:C32H38BrNO7SColore e forma:SolidPeso molecolare:660.62BMS-751324
CAS:<p>BMS-751324: p38α MAPK inhibitor with carbamyl-methyl, esters, phosphate from HPA. Reduces rat arthritis swelling and TNFα.</p>Formula:C32H35N6O10PColore e forma:SolidPeso molecolare:694.63Mcl-1 inhibitor 9
CAS:Mcl-1 Inhibitor 9 (Example 2) is a potent inhibitor of myeloid cell leukemia 1 (Mcl-1), demonstrating anti-tumor activity with an IC50 value of 0.21889 nM.Formula:C32H39ClN2O5SColore e forma:SolidPeso molecolare:599.18AL-GDa62
<p>AL-GDa62, a gastric cancer treatment lead, has EC50 of 3.2 μM (MCF10A-WT) and 2 μM (MCF10A-CDH1 -/-).</p>Formula:C24H28FN3OColore e forma:SolidPeso molecolare:393.5TY 11345
CAS:<p>TY 11345 is a proton pump inhibitor.</p>Formula:C18H18N3NaO2SColore e forma:SolidPeso molecolare:363.41Abarelix acetate
CAS:Abarelix acetate: synthetic GnRHR antagonist, spikes histamine, lowers LH and testosterone temporarily, used in advanced prostate cancer.Formula:C72H95ClN14O14·xC2H4O2Colore e forma:SolidPeso molecolare:1476.14Resolvin D1 methyl ester
CAS:<p>Resolvin D1, from docosahexaenoic acid via 15-/5-lipoxygenase, curbs acute inflammation; EC50 ~30 nM. Its methyl ester may enhance bioavailability.</p>Formula:C23H34O5Colore e forma:SolidPeso molecolare:390.51BRD0418
CAS:<p>BRD0418 acts as an upregulator of TRIB1 expression by leading to reprogramming of hepatic lipoprotein metabolism from adipogenesis to clearance it.</p>Formula:C29H32N2O5Purezza:99.57%Colore e forma:SolidPeso molecolare:488.57Antifungal agent 25
<p>Antifungal agent 25: broad-spectrum, stable in vivo, effective against Candida albicans, including fluconazole-resistant strains.</p>Colore e forma:SolidLDHA-IN-5
CAS:LDHA-IN-5 is a novel and potent inhibitor targeting both glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), designed for the treatment of primaryFormula:C27H22FN7O6S3Colore e forma:SolidPeso molecolare:655.7TLR7/8 antagonist 1
Compound 16c, an imidazoquinoline, is a TLR7/8 agonist; IC50: 3.91 μM (TLR7), 2.19 μM (TLR8); targets TLR-2050 for disease treatment.Formula:C24H27N5O2Colore e forma:SolidPeso molecolare:417.5GZN39838
CAS:GZN39838, a natural Kv1.2 blocker, induces C-type inactivation without blocking the outer pore.Formula:C22H30O6Colore e forma:SolidPeso molecolare:390.47Cilobamine mesylate
CAS:Cilobamine mesylate is a drug which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI) and has stimulant and antidepressant effects.Formula:C18H27Cl2NO4SColore e forma:SolidPeso molecolare:424.38BMT-052
CAS:<p>BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).</p>Formula:C30H17D9F4N6O5Purezza:98%Colore e forma:SolidPeso molecolare:635.61Adafosbuvir
CAS:<p>Adafosbuvir has antiviral activity.</p>Formula:C22H29FN3O10PColore e forma:SolidPeso molecolare:545.457L-2'-Fd4C
CAS:L-2'-Fd4C is an L-nucleoside analogue with both anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity [1].Formula:C9H10FN3O3Colore e forma:SolidPeso molecolare:227.19MAO-B-IN-6
MAO-B-IN-6 is a selective, potent, orally active MAO-B inhibitor (IC50: 0.019 μM). MAO-B-IN-6 is superior to Safinamide both in vitro and in vivo.Colore e forma:SolidCdc7-IN-18
CAS:<p>Cdc7-IN-18 (1-2) inhibits CDC7 enzyme (IC50: 1.29 nM) and COLO205 cell proliferation (IC50: 53.62 nM).</p>Formula:C19H21N5OSColore e forma:SolidPeso molecolare:367.47BMS-554417
CAS:BMS-554417 inhibits IGF-IR/insulin receptors, curbing cell proliferation and tumor growth, with IC50 values of 120 nm–>8.5 μmol/L.Formula:C28H30ClN7O2Colore e forma:SolidPeso molecolare:532.04Asukamycin
CAS:<p>Asukamycin, from S. nodosus asukaensis, is a polyketide antibiotic inhibiting tumor cells by activating caspases 8 and 3.</p>Formula:C31H34N2O7Colore e forma:SolidPeso molecolare:546.61P-gp modulator 1
CAS:P-gp modulator 1 is a high affinity and orally available P-glycoprotein (Pgp) modulatorFormula:C41H72N2O6Purezza:98%Colore e forma:SolidPeso molecolare:689.02Tubulin polymerization-IN-9
CAS:Tubulin-IN-9 inhibits tubulin (IC50: 1.82 μM), halts K562 cells in G2/M, induces apoptosis, and has anti-cancer effects.Formula:C19H19NO5SeColore e forma:SolidPeso molecolare:420.32T01-1
CAS:<p>T01-1, a derivative of camptothecin, is an anticancer agent demonstrating significant anti-proliferative activity.</p>Formula:C26H29N3O6SColore e forma:SolidPeso molecolare:511.59BM635 hydrochloride
<p>BM635 hydrochloride, an MmpL3 inhibitor, strongly blocks Divergent bacteriophage H37Rv (MIC50: 0.08 μM), with doubled in vivo potency.</p>Formula:C25H30ClFN2OColore e forma:SolidPeso molecolare:428.97Tylophorinidine
CAS:<p>Tylophorinidine is an antifungal agent that has shown to inhibit cell growth.</p>Formula:C22H23NO4Colore e forma:SolidPeso molecolare:365.42LSD1-IN-16
<p>LSD1-IN-16 (4b) inhibits LSD1, MAO-A/B; IC50: 0.015-0.366 μM. Halts prostate cancer cell growth; IC50: 15.2 μM.</p>Formula:C20H18N2OSColore e forma:SolidPeso molecolare:334.43Anticancer agent 45
Anticancer agent 46, potent and selective, induces apoptosis, is cytotoxic to cancer cells, with low toxicity to human lymphocytes.Formula:C22H14ClN3O6S2Colore e forma:SolidPeso molecolare:515.95IMP-321
CAS:IMP-321 is a soluble dimeric recombinant form of LAG-3 and first-in-class antigen presenting cell activator.Formula:C56H78N18O14SColore e forma:SolidPeso molecolare:1259.4AD011
AD011, a cACE/NEP inhibitor derived from lenopril-tryptophan, may offer strong anti-hypertensive, cardioprotective benefits.Formula:C27H33N3O5Colore e forma:SolidPeso molecolare:479.57CI-988
CAS:CCK2 (CCK-B) receptor antagonistFormula:C35H42N4O6Purezza:98%Colore e forma:SolidPeso molecolare:614.734-Bromo A23187
CAS:4-Bromo A23187 is a halogenated analog of the calcium ionophore A-23187. 4-Bromo A23187 is a calcium modulator and induces apoptosis in different cells.Formula:C29H36BrN3O6Purezza:98%Colore e forma:SolidPeso molecolare:602.52Sovesudil hydrochloride
Sovesudil (PHP-201) HCl: potent local ROCK inhibitor; targets ROCK I/II (IC50: 3.7/2.3 nM); lowers IOP, non-congesting.Formula:C23H23ClFN3O3Colore e forma:SolidPeso molecolare:443.9Dyrk1A/B-IN-1
Dyrk1A/B-IN-1 (3n) is a potent DYRK1A/B inhibitor, cell-permeable, with Ki values of 67.8 nM (1A) and 237.9 nM (1B), IC50s of 1.1 and 0.8 μM.Formula:C21H17N3O2S2Colore e forma:SolidPeso molecolare:407.51L 668750
CAS:L 668750 is an inhibitor of platelet-activating factor.Formula:C25H34O9SPurezza:98%Colore e forma:SolidPeso molecolare:510.6Rosiptor acetate
CAS:Rosiptor (AQX-1125) activates SHIP1, inhibits Akt, and reduces inflammation and allergy in rodents.Formula:C22H39NO4Purezza:98%Colore e forma:Solid PowderPeso molecolare:381.55LY210073
CAS:<p>LY210073 is an antagonist of the Leukotriene B4 (LTB4) receptor (IC50: 6.2 nM).</p>Formula:C30H28O8Purezza:98%Colore e forma:SolidPeso molecolare:516.54CDK8-IN-11 hydrochloride
CDK8-IN-11 HCl: potent, selective CDK8 inhibitor (IC50: 46 nM), blocks WNT/β-catenin pathway, used in colon cancer research.Formula:C19H16ClF3N4O2Colore e forma:SolidPeso molecolare:424.8
