APIs per la ricerca e le impurità
I principi attivi farmaceutici (API) sono le sostanze nei farmaci responsabili dei loro effetti terapeutici. In questa sezione troverai una vasta gamma di API destinati all'uso in ricerca. Questi composti sono essenziali per lo sviluppo, il test e la validazione di nuove formulazioni farmaceutiche. Presso CymitQuimica, offriamo API di alta qualità per supportare la ricerca nella scoperta e nello sviluppo di farmaci.
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Trovati 66898 prodotti di "APIs per la ricerca e le impurità"
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Keto bisoprolol hydrochloride
CAS:Please enquire for more information about Keto bisoprolol hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C18H30ClNO5Purezza:Min. 95%Peso molecolare:375.9 g/molO3-Desethyl apremilast
CAS:O3-Desethyl apremilast is an experimental drug product that belongs to the class of drug products. This drug product has been shown to be a natural, synthetic and analytical impurity in API. It is also an impurity standard for HPLC analysis. O3-Desethyl apremilast can be used in research and development, as well as niche applications in the pharmaceutical industry.
Formula:C20H20N2O7SPurezza:Min. 95%Colore e forma:PowderPeso molecolare:432.45 g/mol3-Ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl) -6-methylpyridine-3,5-dicarboxylate 2- butenedioate
CAS:3-Ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl) -6-methylpyridine-3,5-dicarboxylate 2- butenedioate is a synthetic compound that has been developed for the treatment of bacterial infections. This drug product is metabolized by hydrolysis to form 3,5-dimethyl 2-(2-(2-(2-(2-(2-(2-(hydroxymethyl)amino)ethoxy) ethoxy)ethoxy)ethoxy)ethoxy)-4,6-dimethylpyridine. The analytical standards for this drug are 3,5-dimethyl 2-(2-(2-(2-(2 (hydroxymethyl)amino)ethoxy)ethoxy)ethoxy)-4,6-dimethylpyridine; 3,5-, 6-, and 8-, 10-, 12-, 14-, 16-, 18-,Formula:C20H23ClN2O5•C4H4O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:522.93 g/mol1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid diethyl ester
CAS:1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid diethyl ester is an API impurity. It is a white or cream powder with a melting point of about 135°C. This impurity can be used as an impurity standard for HPLC applications to determine the purity of drug products. It is also suitable for use as a pharmacopoeia analytical reference material and as a synthetic intermediate in research and development (R&D) studies.Formula:C19H22N2O6Purezza:Min. 95%Colore e forma:Yellow PowderPeso molecolare:374.39 g/mol6'-Methoxy-2'-acetonaphthone
CAS:6'-Methoxy-2'-acetonaphthone is a reactive chemical that can be used as a reagent in organic synthesis. It is an electron-rich aromatic compound and its reactivity is enhanced by electron-donating groups such as -OH, -NH2, or -SH. 6'-Methoxy-2'-acetonaphthone can be used to form new carbon-carbon bonds in the presence of metal catalysts. This reaction can be done in either the presence or absence of a solvent, although the yield is better when carried out in organic solvents. Oxime derivatives are formed as oxidation products during this reaction. Acetylation may also occur, which would produce acetophenones or phenylacetones.Formula:C13H12O2Purezza:Min. 95%Colore e forma:Off-White PowderPeso molecolare:200.23 g/molD-Ala(24)-Semaglutide
D-Ala(24)-Semaglutide is a semaglutide impurity. The amino acid at position 24 has been replaced by the D-form of the amino acid D-alanine (D-Ala). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Formula:C187H291N45O59Peso molecolare:4,113.64 g/molLevonorgestrel EP Impurity P
CAS:Soluble in Chloroform & in Methanol Confirmed
Insoluble in WatePurezza:90% minColore e forma:Off White or Beige SolidPeso molecolare:312.451-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxylic acid methyl ester
CAS:Intermediate in the synthesis of ribavirinFormula:C9H13N3O6Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:259.22 g/molLisinopril EP Impurity E
CAS:Lisinopril EP Impurity E is an impurity of lisinopril, which is a prescription drug used to treat high blood pressure. This impurity was found in a preparative high performance liquid chromatography (HPLC) and mass spectroscopy analysis of the drug. The molecular weight of Lisinopril EP Impurity E was determined to be 317.2 amu, which corresponds to the molecular formula C7H13NO2. The FT-IR spectrum showed that this impurity has an ammonium group at 1859 cm-1 and butanoic acid at 1647 cm-1.Formula:C21H31N3O5Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:405.49 g/molRaloxifene N-oxide
CAS:Raloxifene N-oxide is a synthetic drug product that is used in the treatment of osteoporosis. It belongs to the family of selective estrogen receptor modulators (SERM). Raloxifene N-oxide has been shown to inhibit bone resorption and reduce the risk of vertebral fractures. It also has anti-estrogenic effects, which have been shown to be beneficial for prostate cancer patients who are receiving androgen deprivation therapy. Raloxifene N-oxide is an impurity in the synthesis of raloxifene, which is a drug product with CAS number 195454-31-0. The purity of this compound should be at least 99%.Formula:C28H27NO5SPurezza:Min. 95 Area-%Colore e forma:PowderPeso molecolare:489.58 g/mol2-Acetamido-9-[[2-(acetyloxy)ethoxy]methyl]-6,9-dihydro-1H-purin-6-one
CAS:2-Acetamido-9-[2-(acetyloxy)ethoxy]methyl-6,9-dihydro-1H-purin-6-one (ademetionine) is a prodrug that is metabolized in the liver to form ademetionine. Ademetionine is a potent inhibitor of guanosine deaminase, which is an enzyme that breaks down guanosine into guanine and ammonia. Ademetionine has shown efficacy in cancer treatment and may also be used to treat tuberculosis. The metabolism of this drug takes place in the liver, where it undergoes oxidation by cytochrome P450 enzymes to form the active metabolite ademetionine. Metabolism of this drug can be inhibited by drugs such as trifluoromethanesulfonic acid (TFMS), which are used for the treatment of malaria. TFMS inhibits the formation of ademetionine but does not affect the formationFormula:C12H15N5O5Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:309.28 g/molAtorvastatin methyl ester
CAS:Atorvastatin methyl ester is a statin drug that inhibits the synthesis of cholesterol and other lipids in the body. It is used to reduce high levels of low-density lipoprotein (LDL) cholesterol, which may lead to heart disease or stroke. Atorvastatin methyl ester has been shown to be effective in reducing the uptake of LDL cholesterol into cells by preventing the formation of LDL particles. This drug also decreases the production of biphosphate-containing phospholipids, which are essential for dendritic cell maturation. The crystalline polymorphs have been characterized by X-ray diffraction and microscopy. Impurities can be detected using ultraviolet spectroscopy, infrared spectroscopy, or nuclear magnetic resonance spectroscopy.
Formula:C34H37FN2O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:572.67 g/molMethyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate, racemic
CAS:Methyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate is a particle that is used to treat cardiac arrhythmias. It has been shown to be effective as an antipyretic agent and may also have analgesic properties. Methyl 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate is a white powder that melts at temperatures of about 300°C. This drug can be administered by inhalation in the form of a vaporized liquid. The particle size of this drug is typically less than 10 microns in diameter. Methyl 5-benzoyl-2,3-dihydro-1H pyrrolizine 1 carboxylate can be administered through the respiratory tract as an aerosol or nebulizer. The molecular weight of thisFormula:C16H15NO3Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:269.3 g/molParacetamol Impurity L
Paracetamol Impurity L is a drug product that is used as an analytical standard for the impurity paracetamol. It is found in pharmaceuticals, such as acetaminophen, which is used to relieve pain and reduce fever. Paracetamol Impurity L is a natural compound and has been shown to be metabolically stable in humans. The CAS number for this compound is 619-25-4.Formula:C16H16N2O4Purezza:Min. 95%Peso molecolare:300.31 g/mol5-((tert-Butylamino)methyl)-3-(3-fluoro-(2-morpholinyl)phenyl)oxazolidin-2-one
5-((tert-Butylamino)methyl)-3-(3-fluoro-(2-morpholinyl)phenyl)oxazolidin-2-one (5FAMPO) is a metabolite of the drug product, CAS No. 109467-92-6, and has been synthesized for use as an analytical reference standard and impurity standard in drug development studies. 5FAMPO is a synthetic molecule that has not been found in nature, but is structurally similar to natural molecules. 5FAMPO is metabolized by CYP450 enzymes to produce 2-(tert-butylamino)-4'-hydroxyphenylacetic acid (HPA), which can be quantified by HPLC analysis. 5FAMPO is also used as a research and development compound and pharmacopoeia impurity standard.Formula:C18H26FN3O3Purezza:Min. 95%Peso molecolare:351.42 g/molSemaglutide Impurity 54 (D-Ala 18)
D-Ala(18)-Semaglutide is a semaglutide impurity. The amino acid at position 18 has been replaced by the D-form of the amino acid D-alanine (D-Ala). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Formula:C187H291N45O59Peso molecolare:4,113.64 g/mol(betaS,deltaS)-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5- (1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole- 1-heptanoic acid calcium salt (2:1)
CAS:(betaS,deltaS)-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5- (1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole- 1-heptanoic acid calcium salt (2:1) is a fluorinated derivative of the natural metabolite 2-(4-fluorophenyl)-beta,delta-dihydroxy -5-(1 methylethyl)-3 phenyl 4-[(phenylamino)carbonyl]-1H pyrrole 1 heptanoic acid. It is an enantiomer of the racemate with optical purity > 98%. The compound has been used as a pharmacological and supramolecular chemistry probe for assays and chemosensors.Formula:C66H68CaF2N4O10Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:1,155.34 g/molAtorvastatin lactone
CAS:Atorvastatin lactone is a prodrug for atorvastatin. It is an inhibitor of the enzyme HMG-CoA reductase, which is involved in cholesterol synthesis and reduces LDL cholesterol levels. Atorvastatin lactone is absorbed from the gut into the bloodstream and then converted to atorvastatin, which has a higher potency than atorvastatin lactone. This conversion occurs in the liver by cytochrome P450 enzymes, including cytochrome CYP3A4. The pharmacokinetics of atorvastatin lactone are influenced by drugs that inhibit these enzymes. Atorvastatin and its metabolites are excreted in human serum as glucuronide or sulfate conjugates.Formula:C33H33FN2O4Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:540.62 g/molMethyl 2,2-dithienylglycolate
CAS:Intermediate for tiotropium bromide synthesisFormula:C11H10O3S2Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:254.33 g/molAtorvastatin epoxydione impurity
CAS:Atorvastatin epoxydione impurity (EPI) is a heptanoic, hydrate, diastereoisomer, racemic mixture, enantiomer and impurity of Atorvastatin. The EPI has been minimized in the formulation process by using a novel synthesis route that employs a chiral pyrrole derivative as an intermediate. This minimization has allowed for the elimination of the tautomer and other impurities present in the original compound.
Formula:C26H22FNO4Purezza:Min. 95 Area-%Colore e forma:White PowderPeso molecolare:431.46 g/mol
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