Composti e metaboliti farmaceutici e veterinari

Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.

2-hydroxymethyl benzoic acid is a principal metabolite of the phthalidyl moiety in man.

(S)-b-aminoisobutyric acid is a non-protein amino acid originating from the catabolism of valine and thymine.

Hydroxytyrosol (2-(3,4-Di-hydroxyphenyl)-ethanol) is an active ingredient extracted from the olive. It is one of the …

Phloretin (NSC-407292) is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion …

Prasugrel Hydrochloride (LY 640315 Hydrochloride) is a piperazine derivative and pletelet aggregation inhibitor that is …

1-Dodecanol is an endogenous metabolite and a saturated fatty alcohol from coconut oil fatty acids. …

(-)-Epigallocatechin Gallate (EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. (-)-Epigallocatechin …

Deoxycholic acid sodium salt (Sodium deoxycholate) can activate the G protein-coupled bile acid receptor TGR5 …

3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and …

(-)-(S)-Equol (4',7-Dihydroxyisoflavan) is an orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the …

Solanesol (Betulanonaprenol) is a phytochemical present in tobacco leaf. Starting material for synthesis of co-enzyme …

cis-4-Hydroxy-L-proline is an inhibitor of the synthesis and extracellular deposition of collagen. cis-4-Hydroxy-L-proline could inhibit …

1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates …

2'-Deoxycytidine-5'-monophosphoric acid (2'-Deoxycytidine 5'-monophosphate) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) …

Ursocholic acid, a bile acid found predominantly in bile of mammals.

Maltotriose is an inducer of E. coli maltose regulator, the second most abundant sugar in …

L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) acts as an antioxidant and a stimulator of …

glycine (2-Aminoacetic acid) is a non-essential amino acid. It is found primarily in gelatin and …

All-trans-retinal (Vitamin A aldehyde) is a one of the major vitamin A metabolites in the …

Aminoadipic acid (DL-2-Aminoadipic acid) (2-aminoadipate) is a metabolite in the principal biochemical pathway of lysine. …

Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as …

Chlorogenic acid, as a major phenolic compound in honeysuckle, possesses potential antioxidant, antibacterial, anti-inflammatory, and …

2,5-Furandicarboxylic acid (Dehydromucic Acid) is a normal urinary metabolite in humans. 2,5-Furandicarboxylic acid is also …

Desloratadine (Sch34117) is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine …

1,3,5-Trimethoxybenzene (Phloroglucinol trimethyl ether) is a methoxybenzene carrying methoxy groups at positions 1, 3 and …

Cecropin P1, porcine acetate is an antibacterial peptide found in Hyalophora cecropia and pig intestine.

Hyaluronic acid (hyaluronan) is a glucosaminoglycan consisting of D-glucuronic acid and N-acetyl-D-glucosamine disaccharide units that …

2-Hydroxyisobutyric acid (α-Hydroxyisobutyric acid) is a metabolite of methyl tert-butyl ether (MTBE). MTBE may be …

Indole-3-pyruvic acid is a precursor for the plant growth hormone indole-3-acetic acid.

3-Methylbut-2-enoic acid (Senecioic acid) appears in the urine of patients with 3-Methylcrotonic aciduria, which is …

L-Dihydroorotic acid, also known as (S)-4,5-dihydroorotate or dihydro-L-orotate, belongs to the class of organic compounds …

1,3-Dithiane (1,3-Dithian) is a protected formaldehyde anion equivalent that could serve as a useful labeled …

Levulinic acid (4-Oxovaleric acid), derived from the degradation of cellulose, is a precursor for the …

Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation,and used in skincare products

L-Phenylalanine (3-Phenyl-L-alanine) is an essential amino acid and the precursor of the amino acid tyrosine, …

Nerol (Neryl alcohol) is a monoterpene found in many essential oils, such as lemon balm …

Losartan Carboxylic Acid (E-3174) a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), …

Protocatechualdehyde (3,4-Dihydroxybenzaldehyde), a natural polyphenol compound derived from radix Salviae Miltiorrhizae roots, exhibits diverse biological …

[Leu5]-Enkephalin TFA(58822-25-6(free bas)) (Leucyl-enkephalin) is the most potent δ-receptor ago

α-Lipoic Acid (Alphalipoic acid) inhibits NF-κB-dependent HIV-1 LTR activation. α-Lipoic Acid induces endoplasmic reticulum (ER) …

In cells, D-Glucose 6-phosphate sodium (G6P) is generated when glucose is phosphorylated by hexokinase or …

Palatinose hydrate (6-O-α-D-Glucopyranosyl-D-fructose, Isoma) is a disaccharide having an α(1→6) linkage between D-glucose and D-fructose …

D-Valine (H-D-Val-OH) is the enantiomer of L-Valine.

N-Methyl-D-aspartic acid is an amino acid that, as the D-isomer, is the defining agonist for …

7-Dehydrocholesterol (Provitamin D3) down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.

Glycoursodeoxycholic acid (Ursodeoxycholylglycine) is an acyl glycine and a bile acid-glycine conjugate. It is a …

N-Acetylhistamine acetate is a histamine metabolite. It can be used as a potential biomarker of …

Tauroursodeoxycholate (UR 906), also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that …

2-Oxobutanoic acid (alpha-Ketobutyric Acid) is a product of the lysis of cystathionine. It is also …

2,3-Diaminopropanoic acid hydrochloride (3-Amino-DL-alanine monohydrochloride) is an amino acid amide used as a substrate for …

Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, …

2-(2-Methylbenzamido)acetic acid (O-Toluric acid) is an acyl glycine. Acyl glycines are normally minor metabolites of …

(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride (D-Mannosamine hydrochloride) is a compound used in the development of mannosylated liposomes.

L-Serine (serine) is a non-essential amino acid in humans, L-Serine is present and functionally important …

Guanidinosuccinic acid (GSA) has been identified as a uremic toxin, is a nitrogenous metabolite isolated …

Glycocholic acid (Glycocholate) is a bile acid with anticancer activity. Glycocholic acid targets against pump …

1-Methyl-L-histidine (3-(1-Methylimidazol-4-yl)-L-alanine) is a natural but non-proteinogenic amino acid; employed as index of muscle protein …

Hydroxocobalamin (Vitamin B12a) is a naturally occurring, injectable form of vitamin B12 used as a …

Zymostenol (5a-Cholest-8-en-3b-ol) is a RORγ agonist with an EC50 of 1 μM.Zymostenol is a late …

Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation …

Nε,Nε,Nε-Trimethyllysine chloride (Lys(Me)3-OH Chloride) is a methylated derivative of the amino acid lysine. It is …

Tentoxin, a cyclic peptide produced by phytopathogenic fungi, inactivates the F1 motor in sensitive plants …

4-hydroxyestrone-4-methyl ether (4-Methoxy Estrone) is the methylation of 4-OHE1, which is catalyzed by COMT.

N1,N12-Diacetylspermine dihydrochloride (Diacetylspermine 2HCl) is a diacetylated derivative of Spermine. The occurrence of cancer is …