Modulatori enzimatici
I modulatori enzimatici sono composti che possono aumentare o inibire l'attività degli enzimi, regolando così la velocità delle reazioni biochimiche. Questi modulatori svolgono un ruolo cruciale nel controllo delle vie metaboliche, della segnalazione cellulare e di vari processi fisiologici. I modulatori enzimatici sono ampiamente utilizzati nella ricerca e nello sviluppo di farmaci per studiare le funzioni enzimatiche e sviluppare agenti terapeutici. Presso CymitQuimica, offriamo una gamma completa di modulatori enzimatici di alta qualità per supportare la vostra ricerca nella regolazione enzimatica e nella scoperta di farmaci.
Sottocategorie di "Modulatori enzimatici"
Trovati 649 prodotti per "Modulatori enzimatici".
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Capmatinib
CAS:Selective c-Met kinase inhibitor
Formula:C23H17FN6OPurezza:Min. 95 Area-%Colore e forma:Slightly Yellow PowderPeso molecolare:412.42 g/molSeratrodast - Bio-X ™
CAS:Seratrodast is a thromboxane receptor antagonist that is used to treat asthma. However, this drug does not affect thrombus formation as other thromboxane synthase inhibitors do such as ozagrel.Formula:C22H26O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:354.44 g/mol(Z)-Mycophenolic acid
CAS:(Z)-Mycophenolic acid is an immunosuppressive agent derived from the fermentation of fungi, primarily from the Penicillium species. It functions by inhibiting inosine monophosphate dehydrogenase (IMPDH), an enzyme crucial for de novo purine synthesis. This selective blockade of IMPDH specifically affects lymphocyte proliferation due to their heavy reliance on this pathway for DNA synthesis, thereby exerting its immunosuppressive effects.Formula:C17H20O6Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:320.34 g/molAfatinib - Bio-X ™
CAS:Afatinib is a small molecule that inhibits the activity of cellular kinases that are involved in the progression of cancer. It is an Irreversible inhibitor of three members of the ErbB family. This molecule binds covalently to cysteine 797 residue in HER2 and blocks downstream cellular signalling which inhibits cellular growth and promotes apoptosis. It has been researched for the treatment of non-small cell lung cancer (NSCLC), breast cancer, pancreatic cancer and colorectal cancer.Formula:C24H25ClFN5O3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:485.94 g/molGDC 0941
CAS:Pan-class I phosphatidylinositide 3-kinase (PI3K) inhibitor (IC50 = 3, 33, 3 and 75 nM at catalytic subunits p110α, p110β, p110δ and p110γ respectively). Inhibits proliferation in several cancer cell lines, such as glioblastoma, breast and prostate cancer cells. Has synergistic anti-cancer effect in combination with MEK/ERK kinase inhibitor GDC-0973 (cobimetinib).
Formula:C23H27N7O3S2Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:513.64 g/molMotesanib
CAS:Inhibitor of VEGFR, PDGR, c-Kit and Ret; inhibitor of angiogenesisFormula:C22H23N5OPurezza:Min. 95%Peso molecolare:373.45 g/molSB 239063
CAS:Inhibits p38 MAP kinase; anti-inflammatory; neuroprotectiveFormula:C20H21FN4O2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:368.4 g/molNilotinib HCl monohydrate - Bio-X ™
CAS:Nilotinib is a kinase inhibitor that is used for the treatment of Chronic Myeloid Leukemia (CML). This drug is also used for the treatment of CML that is resistant to imatinib. Nilotinib inhibits the tyrosine kinase activity of the BCR-ABL protein. It also inhibits PDGFR and c-kit.
Formula:C28H22F3N7O•HCl•H2OPurezza:Min. 95%Colore e forma:PowderPeso molecolare:583.99 g/molSivelestat
CAS:Inhibitor of human neutrophil elastase
Formula:C20H22N2O7SPurezza:Min. 95%Peso molecolare:434.46 g/mol(-)-Huperzine A
CAS:Acetylcholinesterase inhibitor; therapy for Alzheimer's diseaseFormula:C15H18N2OPurezza:(%) Min. 98%Colore e forma:PowderPeso molecolare:242.32 g/molCYT 387
CAS:Inhibits JAK1 and JAK2 kinasesFormula:C23H22N6O2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:414.46 g/molSemagacestat
CAS:γ-secretase inhibitor; inhibits notch signaling
Formula:C19H27O4N3Purezza:Min. 95%Peso molecolare:361.44 g/molGC376 sodium
CAS:GC 376 is an inhibitor of the main protease Mpro (3CLpro) in coronaviruses as well as picornaviruses. This broad-spectrum antiviral compound has been used as investigational veterinary drug for treatment of feline infectious peritonitis virus (FIPV) infections. Recent studies also showed that GC 376 inhibits the main protease Mpro (3CLpro) from SARS-CoV-2 with IC50 of 0.03 μM and EC50 of 3.37 μM.
Formula:C21H30N3NaO8SPurezza:Min. 95 Area-%Colore e forma:White PowderPeso molecolare:507.53 g/molMethotrexate
CAS:Methotrexate is a chemotherapeutic and immunosuppressive medication, which is a synthetic analog of folic acid. Its source is through chemical synthesis, mimicking the structure of dihydrofolate in order to exert its effects. Methotrexate acts primarily by inhibiting the enzyme dihydrofolate reductase (DHFR), leading to a decrease in tetrahydrofolate production. This disruption in folate metabolism results in the inhibition of DNA, RNA, and protein synthesis, which affects rapidly dividing cells.Methotrexate is employed broadly in clinical oncology as an antineoplastic agent, particularly in the treatment of leukemias, lymphomas, breast cancer, and osteosarcoma. Additionally, it serves as a cornerstone for managing autoimmune diseases such as rheumatoid arthritis and psoriasis, where it helps modulate the aberrant immune response. The dual role of Methotrexate in oncology and immunosuppression underscores its versatility and critical importance in therapeutic regimens. However, its use demands careful monitoring due to potential adverse effects on non-cancerous cells and organ systems, necessitating precise dosage management and patient evaluation.Formula:C20H22N8O5Colore e forma:Yellow PowderPeso molecolare:454.44 g/molPF 06409577
CAS:Potent agonist of a1β1γ1 5′-adenosine monophosphate-activated protein kinase (AMPK). It binds to the allosteric drug and metabolite (ADaM) site at the α- and β- subunit interface of AMPK. It has potential for the treatment of diabetic nephropathy. PF 06409577 reduces infections caused by flaviviruses, mediated by changes in the metabolism of lipids in host cells.
Formula:C19H16ClNO3Purezza:Min. 95%Colore e forma:White/Off-White SolidPeso molecolare:341.79 g/molMalotilate - Bio-X ™
CAS:Malotilate is a pharmacological agent that is used to treat symptoms of hepatitis, bowel disease, and collagen diseases. This drug reduces collagen synthesis and cell migration activity of fibroblasts in vitro. It also has been shown to facilitate liver regeneration in rats.Formula:C12H16O4S2Purezza:(%) Min. 95%Colore e forma:PowderPeso molecolare:288.39 g/mol(S)-Mephenytoin - Bio-X ™
CAS:(S)-Mephenytoin is a substrate of cytochrome P450 enzyme CYP2C19 (a hydroxylase). It is an effective anticonvulsant that improves control of seizures in patients. According to studies, the drug exhibits a genetic polymorphism in CYP2C19 that results in reduced metabolism in some individuals.Formula:C12H14N2O2Purezza:Min. 97 Area-%Colore e forma:White PowderPeso molecolare:218.25 g/molPLX 4032
CAS:BRAF kinase inhibitor; antineoplasticFormula:C23H18ClF2N3O3SPurezza:Min. 95%Colore e forma:PowderPeso molecolare:489.92 g/molAceclofenac - Bio-X ™
CAS:Acecelofenac is a non-steroidal anti-inflammatory drug that is used in the treatment of osteoarthritis, arthritis, and ankylosing spondylitis. This drug is also a cyclooxygenase inhibitor and works by inhibiting this enzyme so that pain and inflammation is reduced.Formula:C16H13Cl2NO4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:354.18 g/mol
