Product Information
- DADLE
- D-Leucine ,N-[N-[N-(N-L-tyrosyl-D-alanyl)glycyl]-L-phenylalanyl]-
- (2-D-Ala,5-D-Leu)-enkephalin
- 161: PN: US20030176421 PAGE: 54-55 claimedprotein
- 2-D-Alanine-5-D-leucine-enkephalin
- Bw 180
- Bw 180C
- Dadl
- Dadle
- Tyr-D-Ala-Gly-Phe-D-Leu
- See more synonyms
- Tyr-D-Ala-Gly-Phe-D-Leu-OH
- Tyrosyl-D-alanylglycylphenylalanyl-D-leucine
- [D-Ala2-D-Leu5]enkephalin
- [D-Alanine2-Leucine5]enkephalin
- H-Tyr-D-Ala-Gly-Phe-D-Leu-OH
DADLE has generally served as the putative, prototypical δ-opioid receptor ligand. DADLE is more potent and selective than Leu-enkephalin or Met-enkephalin in the MVD versus GPI bioassay systems and more potent and approximately as selective as Leu-enkephalin in binding assays. It shows roughly the same antinociceptive activity as β-endorphin.
Chemical properties
Technical inquiry about: 01-4001508 (D-Ala²,D-Leu⁵)-Enkephalin
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