(D-Trp⁷,Ala⁸,D-Phe¹⁰)-α-MSH (6-11) amide
- (D-Trp7,Ala8,D-Phe10)-.alpha.-MSH (6-11)
- Growth Hormone Releasing Peptide
In search of competitive a-MSH antagonists, the hexapeptide GHRP-6 has been recognized as a selective inhibitor of a-MSH activity in the frog skin bioassay. It is identical in sequence with a growth hormone-releasing peptide analog, (His1,Lys6)-GHRP, which selectively releases GH in vitro and in a wide variety of species in vivo. GHRP-6 also acts as a functional antagonist of somatostatin in the somatotrope cells.
Technical inquiry about: 01-4008401 (D-Trp⁷,Ala⁸,D-Phe¹⁰)-α-MSH (6-11) amide
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