Atrial Natriuretic Factor (1-28) (human)

CAS: 89213-87-6

Ref. 01-4011941

Product Information

• Name: Atrial Natriuretic Factor (1-28) (human)
• Synonyms: Carperitide, Atrial natriuretic factor (99-126), Atriopeptin-28 (human), Ccris 4930, Human atriopeptin(1-28), Human atriopeptin(99-126), L-Seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanylglycylglycyl-L-arginyl-L-methionyl-L-aspartyl-L-arginyl-L-isoleucylglycyl-L-alanyl-L-glutaminyl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-asparaginyl-L-seryl-L-phenylalanyl-L-arginyl-L-tyrosine cyclic(7-23)-disulfide, Sun-4936, Triopeptin (human alpha-component), alpha-Atriopeptin (human), alpha-Human atrial natriuretic hormone, alpha-Human atriopeptin, Atriopeptin-33(rat), 1-de-L-leucine-2-de-L-alanine-3-deglycine-4-de-L-proline-5-de-L-arginine-17-L-methionine-, alpha-Atriopeptin, Anp 1-28, Human, Carperitide Acetate, α-Atrial natriuretic peptide human recombinant

Description

ANP/ANF is synthesized in cardiac myocytes and is primarily released in response to atrial wall stretching and intravascular volume expansion. The peptide signals via the guanylate cyclase-linked natriuretic peptide receptor A (NPR-A) and plays an important role in blood pressure regulation and blood volume homeostasis. ANP/ANF exerts vasodilatory, diuretic, natriuretic, anti-inflammatory, antifibrotic and antimitogenic effects. As BNP, ANP stimulates lipolysis in adipocytes. Millucci et al. studied the aggregation behavior of αANP, which may play a role in congestive heart failure.

• Brand: Bachem

Chemical properties

• Molecular weight: 3080.49
• Formula: C₁₂₇H₂₀₃N₄₅O₃₉S₃
• Purity: 97.80%
• Color/Form: White