Product Information
- Fmoc-Asp(OPp)-OH
- Fmoc-Asp(2-phenylisopropylester)-OH
- Fmoc-Asp(O-2-Phipr)-Oh
An aspartic acid derivative allowing specific side chain deprotection with 1% TFA in dichloromethane. Ocampo et al. applied OPp protection during the synthesis of a peptide-oligonucleotide conjugate and cleaved it with 3% trichloroacetic acid in DCM. The OPp derivative is far less prone towards base-catalyzed aspartimide formation than the OAll, OBzl, or ODmab esters, its stability comes close to the stability of the OtBu ester.
Chemical properties
Technical inquiry about: 01-4019087 Fmoc-Asp(2-phenylisopropyl ester)-OH
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