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CAS 200336-86-3

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Fmoc-Asp(2-phenylisopropyl ester)-OH

Description:
Fmoc-Asp(2-phenylisopropyl ester)-OH is a chemical compound commonly used in peptide synthesis and research. It is a derivative of aspartic acid, where the amino group is protected by a 9-fluorenylmethoxycarbonyl (Fmoc) group, which is a widely used protective group in solid-phase peptide synthesis. The presence of the 2-phenylisopropyl ester indicates that the carboxylic acid group of aspartic acid is esterified, enhancing its lipophilicity and potentially influencing its reactivity and solubility in organic solvents. This compound typically appears as a white to off-white solid and is soluble in organic solvents like dichloromethane and dimethylformamide. Its structure allows for selective deprotection of the Fmoc group under mild basic conditions, facilitating the stepwise assembly of peptides. The compound is utilized in various biochemical applications, including drug development and the study of protein interactions, due to its ability to mimic natural amino acids while providing unique chemical properties.
Formula:C28H27NO6
Synonyms:
  • Fmoc-Asp(2-phenylisopropylester)-OH
  • Fmoc-Asp(O-2-Phipr)-Oh
  • FMOC-ASP(O-2-PHIPR)-OH USP/EP/BP
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-ASPARTIC ACID BETA-2-PHENYLISOPROPYL ESTER
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-4-(2-phenylpropan-2-yloxy)butanoic acid
  • N-Fmoc-L-aspartic acid 4-(2-phenyl-2-propyl) ester
  • FMOC-ASP(2-PHENYLISOPROPYL ESTER)-OH
  • FMoc-Asp(OPp)-OH
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-oxo-4-((2-phenylpropan-2-yl)oxy)butanoic acid
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Asp(OPis)-OH
  • See more synonyms
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