Product correctly added to cart.

discount label
Fmoc-Cys(4-methoxytrityl)-OH
View 3D

Bachem logo

Fmoc-Cys(4-methoxytrityl)-OH

CAS: 177582-21-7

Ref. 01-4025726

1g
250.00 €
5g
956.00 €
Estimated delivery in United States, on Tuesday 11 Jun 2024

Product Information

Name:
Fmoc-Cys(4-methoxytrityl)-OH
Synonyms:
  • Fmoc-Cys(Mmt)-OH
  • N-alpha-(9-fluorenylmethyloxycarbonyl)-S-p-methoxytrityl-L-cysteine
  • (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[(4-methoxyphenyl)-diphenyl-methyl]sulfanyl-propanoic acid
Description:

4-Methoxytrityl (Mmt) is a very acid-sensitive cysteine protecting group that can selectively be removed by 0.5-1.0% TFA in the presence of scavengers, e.g. TES. Protecting groups of the t-butyl type and S-Trt are left intact under these conditions. Cleavage and cyclization can be achieved concomitantly by adding iodine. It can be used in the solid-phase synthesis of cysteine-containing peptides, and further to selectively deprotect a thiol function in order to introduce a labeling group. Rijkers et al. employed p-methoxytrityl protection for obtaining S-palmitoylated peptides on-resin. The high acid lability of Cys(Mmt) was exploited by Roberts et al. to obtain a library of thioether-linked cyclic peptides. Arendt et al. employed Cys(Mmt) for the synthesis of peptides containing cysteic acid by selective deblocking and oxidation of the thiol moiety with performic acid. Mmt is fully stable to HOBt.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Bachem
Long term storage:
Notes:

Chemical properties

Molecular weight:
615.76
Formula:
C38H33NO5S
Purity:
99.1%
Color/Form:
White
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

Technical inquiry about: 01-4025726 Fmoc-Cys(4-methoxytrityl)-OH

Please use instead the cart to request a quotation or an order

If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.

* Mandatory fields.
Welcome to CymitQuimica!We use cookies to enhance your visit. We do not include advertising.

Please see our Cookies Policy for more details or adjust your preferences in "Settings".