Product Information
Name:Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂
Synonyms:
- 7-Methoxycoumarin-4-Acetyl-Pro-Leu-Gly-Leu-Dnp-(2,3-Diaminopropionyl)-Ala-Arg, amide
Brand:Bachem
Description:Mca-PLGL-Dpa-AR-amide is a very sensitive FRET substrate for continuous assays and in situ determination of the matrix metalloproteinase activity. Cleavage at the Gly-Leu bond separates the highly fluorescent Mca group from the efficient 2,4-dinitrophenyl quencher, resulting in an increase in fluorescence intensity. The kcat/Km values for the punctuated metalloproteinase (MMP-7) and for gelatinase (MMP-2), e.g., are 1.7·10⁵ and 6.3·10⁵ M⁻¹s⁻¹, respectively.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1093.16
Formula:C49H68N14O15
Purity:98.7%
Color/Form:Yellow Powder
Technical inquiry about: Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂
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