(Glu²)-TRH

CAS: 85541-78-2

Ref. 01-4026102

Product Information

• Name: (Glu²)-TRH
• Synonyms: Fertilization-Promoting Peptide
• Brand: Bachem
• Description: Fertilization-promoting peptide (FPP), a TRH analog, was previously purified and characterized from both rabbit prostate and human semen. Nanomolar concentrations of this peptide have been shown to enhance capacitation of mouse epididymal spermatozoa with a concomitant increase in fertilizing ability. It was also detected in the thyroid gland. According to a study of Nguyen et al. Pyr-Glu-Pro-NH₂ opposes the cholinergic effect of TRH in the mammalian CNS: Co-perfusion with an equivalent of TRH in the rat hippocampus resulted in a significant attenuation of TRH-induced acetylcholine release.

Chemical properties

• Molecular weight: 354.36
• Formula: C₁₅H₂₂N₄O₆
• Purity: 98.6%
• Color/Form: Whitish Powder