Product Information
- Fertilization-Promoting Peptide
- Pyroglutamyl-glutamyl-proline amide
- Fertilization promoting peptide
- Glp-glu-pronh2
- Pglu-glu-pronh2
- Pyroglutamyl-glutamyl-prolinamide
- Pyroglutamyl-glutamyl-prolineamide
- L-Prolinamide, 5-oxo-L-prolyl-L-alpha-glutamyl-
- 5-oxo-L-prolyl-L-alpha-glutamyl-L-prolinamide
- (Glu2)-TRH
- See more synonyms
- Pyr-Glu-Pro-NH2
Fertilization-promoting peptide (FPP), a TRH analog, was previously purified and characterized from both rabbit prostate and human semen. Nanomolar concentrations of this peptide have been shown to enhance capacitation of mouse epididymal spermatozoa with a concomitant increase in fertilizing ability. It was also detected in the thyroid gland. According to a study of Nguyen et al. Pyr-Glu-Pro-NH₂ opposes the cholinergic effect of TRH in the mammalian CNS: Co-perfusion with an equivalent of TRH in the rat hippocampus resulted in a significant attenuation of TRH-induced acetylcholine release.
Chemical properties
Technical inquiry about: 01-4026102 (Glu²)-TRH
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