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Abz-Arg-Val-Lys-Arg-Gly-Leu-Ala-m-nitro-Tyr-Asp-OH
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Abz-Arg-Val-Lys-Arg-Gly-Leu-Ala-m-nitro-Tyr-Asp-OH

CAS: 174838-79-0

Ref. 01-4026550

1mg
194.00 €
Estimated delivery in United States, on Monday 3 Apr 2023

Product Information

Name:
Abz-Arg-Val-Lys-Arg-Gly-Leu-Ala-m-nitro-Tyr-Asp-OH
Synonyms:
  • Furin Substrate
  • H-2-Abz-Arg-Val-Lys-Arg-Gly-Leu-Ala-3-Nitro-Tyr-Asp-Oh
  • Abz-Arg-Val-Lys-Arg-Gly-Leu-Ala-Tyr(No2)-Asp
Description:

Internally quenched fluorogenic peptide substrate containing anthranilic acid as fluorescent donor and m-nitro-tyrosine as acceptor (quencher). The sequence Abz-RVKRGLAY(NO2)E is based on the sequence of hemagglutinin. The FRET substrate is efficiently cleaved by furin, a subtilisin-like eukaryotic serine endoprotease with Km = 3.8 uM and kcat = 29.3 s-1 (kcat/Km = 7’710’000 M-1s-1). Its kcat/Km value is over 2000-fold higher than that of the commonly used substrate Boc-Arg-Val-Arg-Arg-AMC (I-1645). FRET Substrate for the basic residue-specific yeast aspartyl protease yapsin 1.

Long term storage:
Notes:

Chemical properties

Molecular weight:
1241.37
Formula:
C54H84N18O16
Purity:
94.5%
Color/Form:
Yellow Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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