Product Information
Name:Abz-Arg-Val-Lys-Arg-Gly-Leu-Ala-m-nitro-Tyr-Asp-OH
Synonyms:
- Furin Substrate
Brand:Bachem
Description:Internally quenched fluorogenic peptide substrate containing anthranilic acid as fluorescent donor and m-nitro-tyrosine as acceptor (quencher). The sequence Abz-RVKRGLAY(NO₂)E is based on the sequence of hemagglutinin. The FRET substrate is efficiently cleaved by furin, a subtilisin-like eukaryotic serine endoprotease with Km = 3.8 µM and kcat = 29.3 s-¹ (kcat/Km = 7’710’000 M-¹s-¹). Its kcat/Km value is over 2000-fold higher than that of the commonly used substrate Boc-Arg-Val-Arg-Arg-AMC (I-1645). FRET Substrate for the basic residue-specific yeast aspartyl protease yapsin 1.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1241.37
Formula:C54H84N18O16
Purity:94.5%
Color/Form:Yellow Powder
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