Product Information
Name:Z-Val-Ala-DL-Asp-fluoromethylketone
Synonyms:
- Z-VAD-FMK
Brand:Bachem
Description:zVAD-FMK inhibited apoptosis induced by diverse stimuli. Preincubation of cells with this caspase-1 (ICE) inhibitor (50 µM) almost completely inhibited the formation of large kilobase-pair fragments of DNA, a characteristic biochemical change associated with apoptosis. Z-VAD-FMK was shown to irreversibly inhibit most types of caspases, hence it is also called pan-caspase inhibitor. For a cell-permeable analog see N-1560. Inhibitor of peptide:N-glycanase (PNGase).
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Chemical properties
Molecular weight:453.47
Formula:C21H28FN3O7
Purity:95.0%
Color/Form:Beige Lyophilisate
Technical inquiry about: Z-Val-Ala-DL-Asp-fluoromethylketone
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