Estimated delivery in United States, on Thursday 2 Jan 2025
Product Information
Name:
Z-Val-Ala-DL-Asp-fluoromethylketone
Synonyms:
- Z-VAD-FMK
- L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(carboxymethyl)-3-fluoro-2-oxopropyl]-
- L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(carboxymethyl)-3-fluoro-2-oxopropyl]-, (S)-
- N-[(Benzyloxy)carbonyl]-L-valyl-N-(1-carboxy-4-fluoro-3-oxobutan-2-yl)-L-alaninamide
Description:
zVAD-FMK inhibited apoptosis induced by diverse stimuli. Preincubation of cells with this caspase-1 (ICE) inhibitor (50 µM) almost completely inhibited the formation of large kilobase-pair fragments of DNA, a characteristic biochemical change associated with apoptosis. Z-VAD-FMK was shown to irreversibly inhibit most types of caspases, hence it is also called pan-caspase inhibitor. For a cell-permeable analog see N-1560. Inhibitor of peptide:N-glycanase (PNGase).
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Bachem
Long term storage:
Notes:
Chemical properties
Molecular weight:
453.47
Formula:
C21H28FN3O7
Purity:
95.0%
Color/Form:
Beige Lyophilisate
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: 01-4026865 Z-Val-Ala-DL-Asp-fluoromethylketone
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