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Ac-Trp-Glu-His-Asp-AMC
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Ac-Trp-Glu-His-Asp-AMC

CAS: 189275-74-9

Ref. 01-4027662

5mg
203.00 €Add to cart
Estimated delivery in United States, on Friday 26 Aug 2022

Product Information

Name:
Ac-Trp-Glu-His-Asp-AMC
Synonyms:
  • Ac-WEHD-AMC
  • Acetyl-L-Tryptophyl-L-Glutamyl-L-Histidyl-L-Aspartic Acid Alpha-(4-Methylcoumaryl-7-Amide)
  • Ac-Wehd-Mca
  • Ac-Trp-Glu-His-Asp-7-Amino-4-Methylcoumarin
  • Ac-Trp-Glu-His-Asp-Amc
  • Ac-Trp-Glu-His-Asp-Mca
  • Caspase 1 (Ice) Substrate 3M, Fluorogenic
  • Caspase-1 Substrate (Fluorogenic)
Description:

With a kcat/Km of 3.3 · 106 M-1s-1 the fluorogenic caspase-1 substrate Ac-WEHD-AMC is cleaved 50-fold more efficiently thanAc-YVAD-AMC. This result indicates that the optimal tetrapeptide recognition sequence for caspase-1 is Trp-Glu-His-Asp and not Tyr-Val-Ala-Asp.

Long term storage:
Notes:

Chemical properties

Molecular weight:
784.78
Formula:
C38H40N8O11
Purity:
96.88%
Color/Form:
White
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
GHS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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