(Des-Gly¹⁰,D-Ser(tBu)⁶,Pro-NHEt⁹)-LHRH

CAS: 57982-77-1

Ref. 01-4028150

Product Information

• Name: (Des-Gly¹⁰,D-Ser(tBu)⁶,Pro-NHEt⁹)-LHRH
• Synonyms: Buserelin, [DSer(tBu)6, Des-Gly10] LH-RH, Ethyl Amide, 5-oxoprolylhistidyltryptophylseryltyrosyl-O-tert-butylserylleucyl-N~5~-(diaminomethylidene)ornithyl-N-ethylprolinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-N~5~-(diaminomethylidene)-L-ornithyl-N-ethyl-L-prolinamide, [D-Ser(tert-butyl)6,des-Gly-NH210]-LH-RH ethylamide, [D-Ser6(t-Bu),de-Gly10-NH2]-LH-RH ethylamide, 1-9-(D-Ser(t-butyl))6-LH-releasing hormone ethylamide, 1-9-Luteinizing hormone-releasing factor (swine), 6-[O-(1,1-dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-, Buserelina, Busereline, Etilamide, Hoe 766, Hoe 766A, Ici 123215, Luteinizing hormone-releasing factor (pig), 6-[O-(1,1-dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-10-deglycinamide-, Receptal, Suprefact
• CAS: 57982-77-1

Description

Buserelin is a longer acting synthetic peptide analog of the naturally occurring gonadotropin-releasing hormone (GnRH/LHRH). Substitution of glycine in position 6 by D-serine and that of glycinamide in position 10 by ethylamide, leads to a nonapeptide with a significantly enhanced LHRH effect. The effects of buserelin on follicle-stimulating hormone (FSH) and luteinizing hormone (LH) release are approximately 20 to 170 times higher than those of natural LHRH. CAS Number (buserelin acetate): 68630-75-1.

Chemical properties

• Molecular weight: 1239.44
• Formula: C₆₀H₈₆N₁₆O₁₃
• Purity: 98.0%
• Color/Form: White