Orexin B (human)

CAS: 205640-91-1

Ref. 01-4028263

Product Information

• Name: Orexin B (human)
• Synonyms: Hypocretin-1 (human, mouse, rat)
• Brand: Bachem
• Description: Like orexin A, orexin B (OXB) is a hypothalamic neuropeptide regulating the feeding behavior. Central administration of OXB to rats stimulated food consumption in a similar manner to orexin A, but the effect did not last as long as that of orexin A. The affinity of orexin B for the OX₁ receptor is significantly lower (IC₅₀ = 240 nM) than that of orexin A. Binding affinities for the OX₂ receptor are similar for orexin A and B (IC₅₀ = 38 nM and 36 nM, respectively, for displacement of radiolabeled orexin A bound to the receptor).

Chemical properties

• Molecular weight: 2899.38
• Formula: C₁₂₃H₂₁₂N₄₄O₃₅S
• Purity: 96.3%
• Color/Form: White