Product Information
Name:Orexin B (human)
Synonyms:
- Hypocretin-1 (human, mouse, rat)
Brand:Bachem
Description:Like orexin A, orexin B (OXB) is a hypothalamic neuropeptide regulating the feeding behavior. Central administration of OXB to rats stimulated food consumption in a similar manner to orexin A, but the effect did not last as long as that of orexin A. The affinity of orexin B for the OX₁ receptor is significantly lower (IC₅₀ = 240 nM) than that of orexin A. Binding affinities for the OX₂ receptor are similar for orexin A and B (IC₅₀ = 38 nM and 36 nM, respectively, for displacement of radiolabeled orexin A bound to the receptor).
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Chemical properties
Molecular weight:2899.38
Formula:C123H212N44O35S
Purity:96.3%
Color/Form:White
Technical inquiry about: Orexin B (human)
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