H-Tyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr-OH

CAS: 199999-60-5

Ref. 01-4028287

Product Information

• Name: H-Tyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr-OH
• Synonyms: W9
• Brand: Bachem
• Description: The TNF-α antagonist WP9QY inhibited TNF-α mediated apoptosis and exhibited an IC₅₀ of 5 µM in the binding assay. YCWSQYLCY is the smallest peptidomimetic developed to date that might be used as a lead compound for the next generation of non-peptidic inhibitors. The name WP9QY arises from the binding to the site observed in the TNF-β/TNF-receptor(I) complex designated WP9 and the introduction of the amino acids Gln and Tyr.

Chemical properties

• Molecular weight: 1226.4
• Formula: C₅₈H₇₁N₁₁O₁₅S₂
• Purity: 97.9%