Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂
CAS: 720710-69-0
Ref. 01-4028885
1mg | 299.00 € | ||
5mg | 1,148.00 € |
Product Information
- Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-Nh2
- Mocac-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-Nh2
The N-terminal elongation of the widely used MMP FRET substrate Mca-PLGL-Dpa-AR-NH₂ with a Lys yields a fluorogenic peptide with improved substrate properties. As compared to Mca-PLGL-Dpa-AR-NH₂, the specificity constant (kcat/Km) of the broad-spectrum MMP-substrate Mca-KPLGL-Dpa-AR-NH₂ for collagenases (MMP-1, MMP-8, MMP-13) and MMP-14 is increased two- to ninefold and threefold, respectively, while those for gelatinases and matrilysin remain equally high.
Chemical properties
Technical inquiry about: 01-4028885 Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂
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