GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat)

CAS: 87805-34-3

Ref. 01-4037542

Product Information

• Name: GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat)
• Synonyms: Proglucagon (72-108) (human, bovine, guinea pig, mouse, rat)
• Brand: Bachem
• Description: Glucagon-Like Peptide 1 (GLP-1) is synthesized by posttranslational processing of proglucagon in the intestine and pancreas and plays an important role in metabolic homeostasis. Among the different molecular forms, such as GLP-1 (7-36) amide and GLP-1 (7-37), the function of GLP-1 (1-37) has been unclear. GLP-1 (1-37) was shown to convert intestinal epithelial cells into insulin-producing cells. These observations turned GLP-1 (1-37) into a new promising therapeutic compound for the treatment of diabetes mellitus. In animal models of dilated cardiomyopathy, hypertensive heart failure, and myocardial infarction, GLP-1 has shown a remarkable cardioprotective activity.

Chemical properties

• Molecular weight: 4169.54
• Formula: C₁₈₆H₂₇₅N₅₁O₅₉
• Purity: 97.1%
• Color/Form: White Lyophilisate