TRH

CAS: 24305-27-9

Ref. 01-4038214

Product Information

• Name: TRH
• Synonyms: Prolactoliberin, (Pyro)-<span class="text-smallcaps">L</smallcap>-glutamic acid-<smallcap>L</smallcap>-histidine-<smallcap>L</span>-proline-NH₂, (Pyro)-L-glutamic acid-L-histidine-L-proline-NH2, 252: PN: WO2010033207 SEQID: 378 claimed protein, 5-Oxo-<span class="text-smallcaps">L</smallcap>-prolyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-prolinamide, 83: PN: US20090175821 PAGE: 403 claimed protein, <span class="text-smallcaps">L</smallcap>-Prolinamide, 5-oxo-<smallcap>L</smallcap>-prolyl-<smallcap>L</span>-histidyl-, <span class="text-smallcaps">L</smallcap>-Pyroglutamyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-prolinamide, <span class="text-smallcaps">L</smallcap>-Pyroglutamyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-proline amide, Abbott 38579, Antepan, Fda 1725, L-Pyroglutamyl-L-histidyl-L-prolinamide, L-Pyroglutamyl-L-histidyl-L-proline amide, Lopremone, Prem, Protirelin, Protirelina, Protireline, Relefact TRH, Rifathyroin, Rifotironin, Ro 8-6270/9, Stimu TSH, Synthetic TRF, Synthetic TRH, Synthetic TSH-releasing factor, Synthetic TSH-releasing hormone, Synthetic thyrotropin-releasing factor, Synthetic thyrotropin-releasing hormone, TRF, TSH-releasing factor, TSH-releasing hormone, Thypinone, Thyrefact, Thyroid releasing hormone, Thyroid-stimulating hormone-releasing factor, Thyroliberin, Thyrotropic hormone-releasing factor, Thyrotropic hormone-releasing hormone, Thyrotropic releasing hormone, Thyrotropic-releasing factor, Thyrotropin-releasing factor, Thyrotropin-releasing hormone, Tsh-Rf, L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-, 5-Oxo-L-prolyl-L-histidyl-L-prolinamide

Description

TRH exhibits a variety of biological effects, when injected into humans or animals. Its physiological role appears to be the stimulation of thyrotropin (TSH) and prolactin (PRL) release from the anterior pituitary. Though it was first identified in the hypothalamus as a regulator of the pituitary-thyroid axis, TRH was detected as well by Luo et al. in pancreatic β-cells co-localized with insulin. Application of the hormone reverted hyperglycemia in rats. Moreover, TRH plays an important role in the control of human hair-growth and hair follicle pigmentation.

• Brand: Bachem

Chemical properties

• Molecular weight: 362.39
• Formula: C₁₆H₂₂N₆O₄
• Purity: 98.6%
• Color/Form: Whitish Powder