Product Information
Name:N-(4-Methoxyphenylazoformyl)-Arg-OH · HCl
Synonyms:
- Aaf-Arg-OH
Brand:Bachem
Description:AAFR, substrate for carboxypeptidase B type enzymes. Enzymic removal of the anisylazoformyl (Aaf) moiety is followed by a decrease in substrate absorption at 350 nm (λmax ≈ 350 nm, ε ≈ 19000 M⁻¹ cm⁻¹). The kcat/Km value for hydrolysis by porcine carboxypeptidase B at 25 °C, pH 7.9 (0.05 M Tris buffer) was 1.0 x 10⁶ s⁻¹ M⁻¹. AAFR has been used to measure the TAFI (thrombin activatable fibrinolysis inhibitor, carboxypeptidase U) activation by thrombin and thrombin-thrombomodulin.
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Chemical properties
Molecular weight:372.81
Formula:C14H20N6O4·HCl
Purity:> 99%
Color/Form:Orange Red Powder
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