Calcium-Like Peptide 3
- Calcium-like peptide 3
CALP-3, VKFGVGFK, acts as a calmodulin agonist. The octapeptide interacts with the calmodulin EF-hand motif, the Ca2+-binding site. CALP-3 activates phosphodiesterase in the absence of calcium and inhibits Ca2+-mediated cytotoxicity and apoptosis. CALP-3 is more active than CALP-1. By preventing trypsin activation within pancreatiic acinar cells CALP-3 shows potential therapeutic potential in the treatment of pancreatitis.
Technical inquiry about: 01-4078801 Calcium-Like Peptide 3
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