Product Information
Name:WRW4
Brand:Bachem
Description:Antagonist of formyl peptide receptor-like 1 (FPRL1) signalling. WRW4 inhibits WKYMVm binding to FPRL1 (IC₅₀ 0.23 mM) as well as the intracellular calcium release induced by WKYMVm, MMK-1, amyloid β42, and F peptide. The tryptophan-rich peptide also inhibits FPRL1-mediated signalling in human neutrophils and blocks chemotactic migration and superoxide generation by Aβ42. WRW4 inhibited the activation of FPRL2 by F2L, an FPRL2-selective endogenous agonist, resulting in the complete inhibition of intracellular calcium increase and chemotactic migration.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1104.27
Formula:C61H65N15O6
Purity:95.0%
Color/Form:White Lyophilisate
Technical inquiry about: WRW4
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