01-H-1270 - h-ala-ala-ala-ala-ala-oh | 10183-34-3

Tetraalanine is a substrate for carboxypeptidase P from pig kidneys.

Substrate for B.subtilis D-aminopeptidase.

Non-competitive inhibitor of alanine racemase, Ki 1.71 mM.

[6366-77-4] (net)

The dipeptide Leu-Ala inhibits ubiquitin-mediated protein degradation. It has been shown to act in vitro as an inhibitor of neurite outgrowth of PC12 cells.

Ala-Phe was shown to be an efficient enatioselective catalyst in aldol reactions.

Substrate for human methionine aminopeptidases 1D and 2. For the latter enzyme, Yang et al. determined the kinetic parameters Km 0.38 ± 0.03 mM and kcat 210 ± 5 min⁻¹ at pH 7.5 and 30°C for the tripeptide MAS.

Substrate for bacterial β-aspartylpeptidase.

Substrate for bacterial D-aminopeptidases.

Cyanoalanine may serve as an IR-probe in peptides and proteins for studying site-specfic local electrostatic environments and thereby folding and unfolding processes. This neurotoxic amino acid reversibly inactivates pig heart alanine aminotransferase.