01-L-1070 - h-ala-pna | -

A good substrate for aminopeptidase M (microsomal alanyl aminopeptidase).

AAA-pNA, chromogenic substrate for porcine pancreatic elastase and for astacin, a crayfish zinc-endopeptidase.

Very good substrate for the assay of dipeptidyl aminopeptidase IV (DPP IV). It is also hydrolyzed by the thermosensitive dipeptidyl aminopeptidase yscV.

Substrate for chymotrypsin and tripeptidyl peptidases I and II.

AAP-pNA, chromogenic substrate for dipeptidyl aminopeptidase yscV, a thermosensitive enzyme from yeast and for prolyl tripeptidyl peptidases.

Substrate for dipeptidyl peptidase V (DPPV) from Aspergillus fumigatus.

AFP-pNA, substrate for prolyl tripeptidyl aminopeptidases from the periodontal pathogens Porphyromonas gingivalis and Prevotella nigrescens.

FPA-pNA is cleaved by the sedolisins B, C, and D, tripeptidyl peptidases from Aspergillus fumigatus.

Substrate for membrane alanyl aminopeptidase.

The substrate EALFQ-pNA representing the 2C/3A cleavage site of human rhinovirus-14 (HRV-14) polyprotein was hydrolyzed by human rhinovirus-14 3C protease, which represents an attractive target for antiviral drug development. It exhibited a kcat/Km value of 840 M⁻¹s⁻¹.

Chromogenic substrate for dipeptidyl aminopeptidase II (DPPII), also cleaved by a dipeptidyl peptidase V (DPP V) from Aspergillus fumigatus.

<p>H-beta-Ala-pNA·HBr is a nonlinear material that displays discontinuity, heterogeneity and anisotropy. It is subject to analyses of uniaxial and linear elasticity. The tensile properties of H-beta-Ala-pNA·HBr are linear and the material displays a nonlinear behavior in extension. H-beta-Ala-pNA·HBr has been used for applications such as tissue engineering due to its high surface area, which increases the probability of cell adhesion.</p>

<p>H-Ala-Ala-Ala-pNA • HCl is a porcine pancreatic elastase inhibitor. It is a chromogenic substrate that inhibits the proteolytic activity of elastase by binding to the active site and blocking its access to the peptide bond. H-Ala-Ala-Ala-pNA • HCl is used as an enzyme inhibitor in biochemistry and molecular biology research, and has been shown to inhibit enzymatic activity of human leukocyte elastase. The peptide is also a substrate for astacin, which cleaves it at the Cys residue.</p>