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B581, N-[(S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methyl-butyl]-Phe-Met-OH, Farnesyltransferase inhibitor
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B581, N-[(S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methyl-butyl]-Phe-Met-OH, Farnesyltransferase inhibitor

CAS: 149759-96-6

Ref. 01-N-1390

5mg
414.00 €Add to cart
25mg
1,467.00 €Add to cart
Estimated delivery in United States, on Wednesday 15 Dec 2021

Product Information

Name:
B581, N-[(S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methyl-butyl]-Phe-Met-OH, Farnesyltransferase inhibitor
Synonyms:
  • B581, N-[(S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methyl-butyl]-Phe-Met-OH, Farnesyltransferase inhibitor
  • <span class="text-smallcaps">L</smallcap>-Methionine, N-[(2S)-2-[[(2R)-2-amino-3-mercaptopropyl]amino]-3-methylbutyl]-<smallcap>L</span>-phenylalanyl-
  • <span class="text-smallcaps">L</smallcap>-Methionine, N-[N-[2-[(2-amino-3-mercaptopropyl)amino]-3-methylbutyl]-<smallcap>L</span>-phenylalanyl]-, [S-(R*,S*)]-
  • B 581
  • Cys-((R))-Val-((R))-Phe-Met
  • Ftase Inhibitor I
  • H-Cys-(R)-Val-(R)-Phe-Met-Oh
  • N-[(2S)-2-[[(2R)-2-Amino-3-mercaptopropyl]amino]-3-methylbutyl]-<span class="text-smallcaps">L</smallcap>-phenylalanyl-<smallcap>L</span>-methionine
  • N-[(2S)-2-{[(2R)-2-amino-3-sulfanylpropyl]amino}-3-methylbutyl]-L-phenylalanyl-L-methionine
  • N-[(S)-2-((R)-2-Amino-3-Mercapto-Propylamino)-3-Methyl-Butyl]-Phe-Met-Oh
  • See more synonyms
  • N-[2(S)-(2(R)-2-Amino-3-Mercaptopropylamino)-3-Methylbutyl]-L-Phenylalanyl-L-Methionine
  • N-[2(S)-[2(R)-Amino-3-Mercaptopropylamino]-3-Methyl-Butyl]-Phe-Met
  • N-[2(S)-[2(R)-Amino-3-Mercaptopropylamino]-3-Methylbutyl]-Phe-Met-Oh
Description:
B581, Cys-psi(CH2NH)-Val- psi[CH2NH]-Phe-Met is a farnesyltransferase (FTase) inhibitor of special stability and membrane permeability. Due to its high selectivity, B581 is more than 30-fold more active against FTase (IC50 = 21 nM in vitro) than against geranylgeranyltransferase (GGTase). Inhibitors of the farnesyltransferase are potential candidates for the development of anticancer drugs.
Long term storage:
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Chemical properties

Molecular weight:
470.23853
Formula:
C22H38N4O3S2
Purity:
95.7%
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Hazard Info

UN Number:
EQ:
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Forbidden to fly:
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LQ:

Technical inquiry about: 01-N-1390 B581, N-[(S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methyl-butyl]-Phe-Met-OH, Farnesyltransferase inhibitor

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