2-Iodoacetamide, 98%, stab. with ca 5-8% water

CAS: 144-48-9

Ref. 02-A14715

Product Information

• Name: 2-Iodoacetamide, 98%, stab. with ca 5-8% water
• Synonyms: iodoacetamide, 2-Iodacetamid, 2-Iodoacetamida, 2-Iodoacetamide, Acetamide, Iodo, Deltop, Iodoacetamide, Monoiodoacetamide, Nsc 9581, Surauto, α-Iodoacetamide, Acetamide, 2-iodo-, Acetamide, 2-iodo-

Description

Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 184.96
• Formula: C₂H₄INO
• Purity: 5-8%
• Color/Form: White to cream to yellow to pale brown, Crystals or powder or crystalline powder
• InChI key: PGLTVOMIXTUURA-UHFFFAOYSA-N