Glybenzcyclamide, 99%

CAS: 10238-21-8

Ref. 02-B21459

Product Information

• Name: Glybenzcyclamide, 99%
• Synonyms: glyburide glimide semi-euglucon abbenclamide gilemal glibenclamid heumann glibenclamid-ratiopharm glycolande renabetic semi-daonil, 1-[4-[2-(5-Chloro-2-methoxybenzamido)ethyl]phenylsulfonyl]-3-cyclohexylurea, 1-[[-p-[2-(5-Chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-cyclohexylurea, 1-[p-2-(5-Chloro-o-anisamido)ethylphenylsulfonyl]-3-cyclohexylurea, 5-Chloro-N-(2-(4-((((Cyclohexylamino)Carbonyl)-Amino)Sulfonyl)Phenyl)-Ethyl)-2-Methoxybenzamide, 5-Chloro-N-(2-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenyl)ethyl)-2-methoxybenzamide, 5-chloro-2-methoxy-N-[2-[4-(phenylcarbamoylsulfamoyl)phenyl]ethyl]benzamide, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, Abbenclamide, Adiab, Amglidia, Antibet, Apo-Glibenclamide, Azuglucon, Bastiverit, Benclamin, Betanase, Betanaz, Calabren, Cytagon, Daonil, Debtan, Dia-basan, Diaben, Diabeta, Diabiphage, Diazet, Dibelet, Duraglucon, Euglucan, Euglucon, Euglykon, Gilemal, Gl, Glamide, Gliban, Gliben, Glibenclamid, Glibenclamida, Glibenclamide, Glibenil, Glibens, Glibesyn, Glibet, Glibetic, Glibil, Glibomet, Gliboral, Glicem, Glicuformine, Glidiabet, Glimel, Glimide, Glimidstada, Glisulin, Glitisol, Glubate, Gluben, Glucal, Gluco-Tabinen, Glucobene, Glucohexal, Glucolon, Glucomid, Glucoremed, Glucoven, Glukovital, Glustat, Gluvans, Glyben, Glybenclamide, Glyburide, Glyburine, Glycolande, Glycomin, Glyform, Glymet, Glynase, Hemi-Daonil, Humedia, Libanil, Maninil, Med-Glionil, Melix, Micronase, Miglucan, N-4-[2-(5-Chloro-2-methoxybenzamido)ethyl]phenylsulfonyl-N'-cyclohexylurea, N-[4-(β-(2-Methoxy-5-chlorobenzamido)ethyl)benzosulfonyl]-N'-cyclohexylurea, N-[4-[β-(2-Methoxy-5-chlorobenzamido)ethyl]benzenesulfonyl]-N'-cyclohexylurea, Norboral, Orabetic, Pira, Prodiabet, Renabetic, Semi-Daonil, Semi-Euglucon, Sugril, Suraben, Tiabet, Wuglucon, Yuglucon

Description

Glyburide (Glibenclamide) is a sulfonylurea compound that modulates insulin production. Sulfonylureas bind to ATP-dependent K+ channels in beta cells of the pancreas, depolarizing them and stimulating the release of Ca2+, which in turn stimulates insulin production. Glyburide (Glibenclamide) is an ATP-dependent K+ channel (KIR6, KATP) and CFTR Cl- channel blocker. This compound inhibits recombinant CFTR Cl- channels (IC50 = 20 M). This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 494.00
• Formula: C₂₃H₂₈ClN₃O₅S
• Purity: 99%
• Color/Form: White, Crystals or powder or crystalline powder
• InChI key: ZNNLBTZKUZBEKO-UHFFFAOYSA-N