6(5H)-Phenanthridinone, 96%

CAS: 1015-89-0

Ref. 02-B25187

Product Information

• Name: 6(5H)-Phenanthridinone, 96%
• Synonyms: 5H-phenanthridin-6-one, 5H-Phenanthridin-6-one, 6(5H)-Phenanthridone, 6-Phenanthridinol, 6-Phenanthridinone, 6-Phenanthridone, NSC 11021, NSC 40943, NSC 61083, Phenanthridinone, Pj 97A, Wd 99-004344, phenanthridin-6(5H)-one, phenantridine-6(5H)-one

Description

6(5H)-Phenanthridinone is used as a probe into the role of PARP in cellular response to irradiation. Treatment of cells with 6(5H)-Phenanthridinone and various DNA-damaging agents showed a resistance to apoptosis. It acts as a reactant in the synthesis of 5,6-dihydrophenanthridine sulfonamides, oxidative coupling with diphenylacetylene, direct copper acetate-catalyzed N-cyclopropylation of cyclic amides. It is used as HIV-1 integrase inhibitor. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 195.22
• Formula: C₁₃H₉NO
• Purity: 96%
• Color/Form: Powder, Cream to pale brown
• InChI: InChI=1S/C13H9NO/c15-13-11-7-2-1-5-9(11)10-6-3-4-8-12(10)14-13/h1-8H,(H,14,15)
• InChI key: RZFVLEJOHSLEFR-UHFFFAOYSA-N
• SMILES: O=c1[nH]c2ccccc2c2ccccc12