Orotic acid, anhydrous, 97%

CAS: 65-86-1

Ref. 02-B25349

Product Information

• Name: Orotic acid, anhydrous, 97%
• Synonyms: orotic acid 奥拉米特 orotsaeure orazamide, 1, 2, 3, 6-Tetrahydro-2, 6-dioxo-4-pyrimidine carboxylic acid, 1,2,3,6-Tetrahydro-2,6-Dioxopyrimidine-4-Carboxylic Acid, 1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidine carboxylic acid, 1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid, 2,4-Dihydroxypyrimidine-6-carboxylic acid, 2,4-Dioxo-1H-pyrimidine-6-carboxylic acid, 2,6-Dihydroxy-4-pyrimidinecarboxylic acid, 2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, 2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid~Uracil-4-carboxylic acid, 2-Hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid, 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, 6-Carboxyuracil, 6-Uracilcarboxylic acid, Acide orotique, Acido Orotico, Animal galactose factor, Nsc 79560, Nsc 9791, Orodin, Orotic Acid Anhydrous, Orotic Acid Free Acid Anhydrous Plant*Cell Cultur, Orotonin, Orotsaeure, Orotsaure, Oroturic, Orotyl, Vitamin B13, Vitamin B₁₃, Whey factor, Orotic acid

Description

Orotic acid is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5?-phospho-α-d-ribose 1?-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5?-monophosphate (OMP). It is used as a starting material for the potential commercial bioproduction of uridine 5?-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. It may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 156.10
• Formula: C₅H₄N₂O₄
• Purity: 97%
• Color/Form: White, Powder
• InChI: InChI=1S/C5H4N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h1H,(H,9,10)(H2,6,7,8,11)
• InChI key: PXQPEWDEAKTCGB-UHFFFAOYSA-N
• SMILES: O=C(O)c1cc(=O)[nH]c(=O)[nH]1