cis-4-Hydroxy-L-proline, 99%

CAS: 618-27-9

Ref. 02-H27194

Product Information

• Name: cis-4-Hydroxy-L-proline, 99%
• Synonyms: (2S,4S)-(-)-4-Hydroxypyrrolidine-2-carboxylic acid, H-cis-Hyp-OH, (2S,4S)-(-)-4-Hydroxy-2-pyrrolinecarboxylic acid, (2S,4S)-4-Hydroxyproline, (2S,4S)-4-hydroxypyrrolidine-2-carboxylic acid, (4S)-4-Hydroxy-<span class="text-smallcaps">L</span>-proline, (S)-allo-Hydroxyproline, 4(S)-Hydroxy-2(S)-pyrrolidinecarboxylic acid, 4-cis-Hydroxy-<span class="text-smallcaps">L</span>-proline, <span class="text-smallcaps">L</span>-Allohydroxyproline, <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, (4S)-, <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, cis-, <span class="text-smallcaps">L</span>-Proline, allo-hydroxy-, <span class="text-smallcaps">L</span>-allo-4-Hydroxyproline, <span class="text-smallcaps">L</span>-allo-Hydroxyproline, <span class="text-smallcaps">L</span>-cis-4-Hydroxyproline, H-Cis-Hyp-OH, NSC 206274, Proline, 4-allo-hydroxy-, Proline, 4-allo-hydroxy-, <span class="text-smallcaps">L</span>-, allo-4-Hydroxyproline, allo-<span class="text-smallcaps">L</span>-Hydroxyproline, allo-Hydroxy-<span class="text-smallcaps">L</span>-proline, cis-4-Hydroxy-<span class="text-smallcaps">L</span>-proline, cis-4-Hydroxyproline, cis-Hydroxyproline, L-Proline, 4-hydroxy-, cis-, L-Proline, 4-hydroxy-, (4S)-, (4S)-4-Hydroxy-L-proline, Proline, 4-allo-hydroxy-, L-

Description

cis-4-Hydroxy-L-proline (CHP) is a proline analog that inhibits collagen synthesis and has been used as an anticancer compound. CHP blocked myotube formation and expression of sarcomeric myosin heavy chain in C2C12 murine skeletal muscle cells. CHP inhibited proliferation of murine Panc02 pancreatic carcinoma cell line3 and rat pancreatic carcinoma cell line DSL6A. cis-4-Hydroxy-L-proline and other hydrosyl-L-prolines are important intermediates for chiral synthesis of potential drugs. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 131.13
• Formula: C₅H₉NO₃
• Purity: 99%
• Color/Form: Powder, White to cream