(-)-Epicatechin gallate

CAS: 1257-08-5

Ref. 02-J60814

Product Information

• Name: (-)-Epicatechin gallate
• Synonyms: epicatechin gallate (-)-epicatechin 3-O-gallate, (-)-Epicatechin 3-O-gallate, (-)-Epicatechin 3-gallate, (-)-Epicatechol gallate, (-)-epi-Catechin 3-O-gallate, (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, (2R,3S)-2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-3,4-dihydro-2H-chromen-5-yl 3,4,5-trihydroxybenzoate, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, 3-Galloyl-(-)-epicatechin, 3-Galloyl-(2R,3R)-(-)-Epicatechin, 3-O-Galloyl-(-)-epicatechin, 3-O-Galloylepicatechin, <span class="text-smallcaps">L</span>-Epicatechin gallate, Benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester, Benzoic acid, 3,4,5-trihydroxy-, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester, (2R-cis)-, ECG, Epicatechol 3-gallate, Gallic acid, 3-ester with epicatechol, (-)-, L-Ecg

Description

(-)-Epicatechin gallate is used as an antioxidant investigated as an adjunct treatment of some methyicillin resistant bacteria. Epicatechin gallate binds to the cell membrane in methicillin-resistant Staphylococcus aureus which decreases the fluidity of the bilayer and induces changes in gene expression. One of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 442.38
• Formula: C₂₂H₁₈O₁₀
• Color/Form: White to off-white, Powder
• InChI key: LSHVYAFMTMFKBA-TZIWHRDSSA-N