6-Azauridine

CAS: 54-25-1

Ref. 02-J61309

Product Information

• Name: 6-Azauridine
• Synonyms: 6-Azauracil riboside, 2-beta-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione, 1,2,4-Triazine-3,5(2H,4H)-dione, 2-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, 2-(beta-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione, 2-(beta-D-ribofuranosyl)-1,2,4-triazine-3,5-diol, 2-pentofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione, 2-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione, 2-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-as-triazine-3,5(2H,4H)-dione, 6-AzUr, 6-Azauracil 1-riboside, 6-Azauracil-β-<span class="text-smallcaps">D</span>-riboside, 6-Azuridine, Azauridine, Fsl 0296, NSC 32074, Rib-Azauracil, Riboazauracil, as-Triazine-3,5(2H,4H)-dione, 2-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, as-Triazine-3,5(2H,4H)-dione, 2-β-D-ribofuranosyl-, 2-β-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione, 1,2,4-Triazine-3,5(2H,4H)-dione, 2-β-D-ribofuranosyl-

Description

6-Azauridine can be applied in antiviral studies. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis. It is also used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 245.19
• Formula: C₈H₁₁N₃O₆