(+/-)-Equol

CAS: 94105-90-5

Ref. 02-J61383

Product Information

• Name: (+/-)-Equol
• Synonyms: 4',7-Isoflavandiol, (3S)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol, (?à)-Equol, (S)-3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol, 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxyphenyl)-, 3,4-Dihydro-3-(4-hydroxyphenyl)-(S)-2H-1-benzopyran-7-ol, 3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol, 3-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol, 7,4'-Homoisoflavane, 7,4'-Isoflavandiol, Ccris 9222, NV 07α, NV07a, S-Equol, (±)-Equol

Description

(±)-Equol exhibits EC50 values of 200 and 74 nM for human ERα and ERβ, respectively and induces breast cancer cell proliferation in vitro at concentrations as low as 100 nM. It is a weak estrogenic agonist, and competitive inhibitor of 17β-estradiol at the estradiol receptor. It inhibits 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced neoplastic cell transformation by targeting the MEK/ERK/p90RSK/activator protein-1 signalling pathway. It functions as a DHT blocker. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 242.27
• Formula: C₁₅H₁₄O₃
• Color/Form: Crystals or powder or crystalline powder or granules, White to pale cream