(+)-1-Deoxynojirimycin

CAS: 19130-96-2

Ref. 02-J62602

Product Information

• Name: (+)-1-Deoxynojirimycin
• Synonyms: 1-deoxynojirimycin, (2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol, (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, (2R,3R,4R,5S)-2-Hydroxymethyl-3,4,5-Trihydroxypiperidine, 1,5-Dideoxy-1,5-Imino-D-Glucito, 1,5-Dideoxy-1,5-Imino-D-Glucitol, 1,5-Dideoxy-1,5-imino-<span class="text-smallcaps">D</span>-glucitol, 1-Deoxy-Nojirimyci, 1-Deoxynojirimicin, 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2R,3R,4R,5S)-, 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, [2R-(2α,3β,4α,5β)]-, 5-Amino-1,5-Dideoxy-D-Glycopyranose, 5-Amino-1,5-dideoxy-<span class="text-smallcaps">D</span>-glucopyranose, 5-Dideoxy-5-Amino-D-Glucopyranos, 5-Piperidinetriol(2R-(2Alpha,3Beta,4Alpha,5Beta))-2-(Hydroxymethyl)-4, <span class="text-smallcaps">D</span>-1-Deoxynojirimycin, <span class="text-smallcaps">D</span>-Glucitol, 1,5-dideoxy-1,5-imino-, BAY-h 5595, Deoxynojirimycin, Duvoglustat, Glucopyranose, 5-amino-1,5-dideoxy-, <span class="text-smallcaps">D</span>-, Moranolin, Moranoline, Nojirimycin, 1-deoxy-

Description

An alpha-glucosidase inhibitor. Interferes with normal processing of N-linked glycoproteins.(+)-1-Deoxynojirimycin acts as an inhibitor of alfa-glucosidase I and II and maltase-glucoamylase. It also inhibits mammalian glucosidase, intestinal and lysosmal, beta-glucosidase from sweet almonds, pancreatic alfa-amylase and amyloglucosidase. Further, it serves as a enzyme enhancer for the treatment of Fabry and Pompe disease. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 163.17
• Formula: C₆H₁₃NO₄
• Color/Form: White to off-white, Powder
• InChI key: LXBIFEVIBLOUGU-JGWLITMVSA-N