Norfloxacin

CAS: 70458-96-7

Ref. 02-J62652

Product Information

• Name: Norfloxacin
• Synonyms: norfloxacin sebercim norfloxacin (substance) NFLX norfloxacine norfloxacino norfloxacinum norfloxacin (product) barazan fulgram, 1,4-Dihydro-1-Ethyl-6-Fluoro-4-Oxo-7-(1-Piperazinyl)-3-Quinolinecarboxylic Acid, 1-Ethyl-6-Fluoro-4-Oxo-7-Piperazin-1-Yl-Quinoline-3-Carboxylic Acid, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid, 1-Ethyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, 1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid, 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid, 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid, 2-Hydroxypropanoic Acid, 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, 4803P, Am 715, Amicrobin, Baccidal, Barazan, Barotham, Chibroxin, Chibroxine, Chibroxol, Esclebin, Floxacin, Floxacin 400, Fulgram, Gonorcin, Lexinor, Mk 0366, N-Demethylpefloxacin, N-Desmethylpefloxacin, Neofloxacin, Neofloxin, Noflo, Nofocin, Nolicin, Noracin, Noraxin, Norbid, Norflox, Norflox 400, Norfloxacin Bayvit, Norfloxacine, Norfloxacine EG, Norfloxacine Ratiopharm, Norfloxacine Teva, Norfloxacino, Norfloxin, Norilet, Normax, Norocin, Noroxacine, Noroxin, Noroxine, Norphloxacine, Norxacin, Renosept, Sebercim, Spectrama, Urekacin, Uriflox, Uroflox, Urotrobel, Uroxacin, Utin, Utinor, Zoroxin

Description

It finds it application as a fluorinated quinolone antibacterial. It is clinically used to treat urinary tract infections and prostatitis. In neutrophils from cirrhotic subjects, norfloxacin increases expression of IL-10 and heme oxygenase 1 (HO-1) and decreases expression of pro-inflammatory cytokines. Additionally, when complexed with gold(III), norfloxacin binds DNA and inhibits cellular proliferation in several cancer cell lines. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 319.34
• Formula: C₁₆H₁₈FN₃O₃
• Color/Form: Cream to yellowish, Crystalline powder
• InChI key: OGJPXUAPXNRGGI-UHFFFAOYSA-N