Thiamphenicol

CAS: 15318-45-3

Ref. 02-J63575

Product Information

• Name: Thiamphenicol
• Synonyms: thiamphenicol armai (TN) thiocymetin (TN) (+)-thiamphenicol 甲砜霉素, (2′R,3′R)-Thiamphenicol, 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide, 2,2-dichloro-N-{1,3-dihydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide, 8065Cb, <span class="text-smallcaps">D</span>-Thiocymetin, <span class="text-smallcaps">D</span>-Thiophenicol, <span class="text-smallcaps">D</span>-d-threo-2-Dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-propanediol, <span class="text-smallcaps">D</span>-threo-(1R,2R)-1-(p-Methylsulfonylphenyl)-2-dichloroacetamido-1,3-propanediol, Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-, Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-, [R-(R*,R*)]-, Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-(methylsulfonyl)phenethyl]-, <span class="text-smallcaps">D</span>-threo-(+)-, Dextrosulphenidol, Methylsulfonyl chloramphenicol, NSC 522822, Thiocymetin, Thiophenicol, Tirsan, Win 5063-2
• CAS: 15318-45-3

Description

Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 356.21
• Formula: C₁₂H₁₅Cl₂NO₅S
• Color/Form: White to yellow, Powder or crystals or crystalline powder
• InChI key: OTVAEFIXJLOWRX-NXEZZACHSA-N