Clotrimazole

CAS: 23593-75-1

Ref. 02-J63895

Product Information

• Name: Clotrimazole
• Synonyms: 1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole, 1-(o-Chlorotrityl)imidazole, (2-Chlorophenyl)diphenyl-1-imidazolylmethane, 1-(o-Chlorophenyldiphenylmethyl)imidazole, 1H-Imidazole, 1-[(2-chlorophenyl)diphenylmethyl]-, 1[(2-chlorophenyl)diphenylmethyl]-1H-imidazole, Agisten, Bay 5097, Bay 5907, Bay-B 5097, Canesten, Canifug, Clotrimazol, Clotrimazole ZnSO4 complex, Desamix F, Diphenyl(2-chlorophenyl)(1-imidazolyl)methane, Empecid, Femcare, Gyne-Lotrimin, Gyne-Lotrimin 7, Imidazole, 1-(o-chloro-α,α-diphenylbenzyl)-, Locasten, Lotrimin, Lotrimin AF Cream, Lotrimin AF Solution, Lotrimin Jock-Itch Cream, Lotrimin Jock-Itch Lotion, Monobaycuten, Mycelex, Mycelex 7, Mycelex G, Mycelex OTC, Mycelex Troche, Mycofug, Mycosporin, Nsc 257473, Pedisafe, Plimycol, Rimazole, Tibatin, Trimysten, Veltrim

Description

Clotrimazole is an imidazole derivative and an antifungal compound and a CYP (cytochrome P450) inhibitor. Clotrimazole has been shown to block the intermediate-conductance, IK1 channels (Ca2+ activated K+ channels), in cells such as erythrocytes. In vitro studies of various yeast strains have demonstrated susceptibility to clotrimazole. Clotrimazole is an activator of MB67 and an inhibitor of CYP3A4 and CYP51A1. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 344.84
• Formula: C₂₂H₁₇ClN₂