Guanidine thiocyanate, Molecular Biology Grade

CAS: 593-84-0

Ref. 02-J65104

Product Information

• Name: Guanidine thiocyanate, Molecular Biology Grade
• Synonyms: guanidinium thiocyanate, 2-(Cyanosulfanyl)Guanidine, Buffer AVL, Buffer ML, Buffer MTL, Buffer RLT, GTC, Guanidine Thiocyanate (1:1), Guanidine isothiocyanate, Guanidine, monothiocyanate, Guanidinium Isothiocyanate, Guanidinium thiocyanate, NSC 2119, Thiocyanic acid, compd. with guanidine (1:1), Guanidine thiocyanate

Description

Guanidine thiocyanate is used for RNA isolation and can solubilize proteins. When the compound is used to solubilize proteins it can be removed by dialysis against urea without difficulty. The hybridization of guanidine thiocyanate-solubilize hepatocytes can be used as a method to quantify mRNA from hepatocytes. Blood sample lysate stored in guanidine thiocyanate has been shown to maintain nucleic acid integrity. Research describes guanidine thiocyanate to be ineffective for RNA isolation of plant tissue with a high levels of secondary metabolites and storage proteins. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 118.16
• Formula: C₂H₆N₄S
• Color/Form: White to pale yellow, Crystalline powder
• InChI key: ZJYYHGLJYGJLLN-UHFFFAOYSA-N