CAS 593-84-0

Guanidine thiocyanate

Description:

Guanidine thiocyanate is a colorless, hygroscopic solid with the chemical formula CH5N3S. It is primarily known for its role as a chaotropic agent, which disrupts hydrogen bonding in water and proteins, making it useful in molecular biology, particularly in the extraction of nucleic acids. The substance is soluble in water and has a relatively high solubility in organic solvents, which enhances its utility in various biochemical applications. Guanidine thiocyanate is also characterized by its ability to denature proteins, facilitating the release of nucleic acids from cellular structures. It has a relatively low toxicity but should be handled with care due to its potential irritant properties. In laboratory settings, it is often used in conjunction with phenol and chloroform for RNA and DNA isolation. Its stability under a range of conditions makes it a valuable reagent in research and diagnostic applications. Proper storage in a cool, dry place is recommended to maintain its efficacy.

Formula: CH₅N₃·CHNS

InChI: InChI=1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H

InChI key: InChIKey=ZJYYHGLJYGJLLN-UHFFFAOYSA-N

SMILES: C(#N)S.C(=N)(N)N

Synonyms:

• 2-(Cyanosulfanyl)Guanidine
• Buffer AVL
• Buffer ML
• Buffer MTL
• Buffer RLT
• GTC
• Guanidine Thiocyanate (1:1)
• Guanidine isothiocyanate
• Guanidine, monothiocyanate
• Guanidinium Isothiocyanate
• Guanidinium thiocyanate
• NSC 2119
• Thiocyanic acid, compd. with guanidine (1:1)

Guanidine Thiocyanate [for Biochemical Research]

CAS: 593-84-0

Formula: CH₅N₃·CHNS

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 118.16

Ref: 3B-G0360

Guanidine Thiocyanate

CAS: 593-84-0

Formula: CH₅N₃·CHNS

Purity: >99.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 118.16

Ref: 3B-G0230

Guanidine thiocyanate, Molecular Biology Grade

CAS: 593-84-0

A protein denaturant

Formula: C₂H₆N₄S

Color and Shape: White to pale yellow, Crystalline powder

Molecular weight: 118.16

Ref: 02-J65104

Guanidine thiocyanate

CAS: 593-84-0

Guanidine thiocyanate

Formula: ·CHNS·CH₅N₃

Purity: >99.0%

Color and Shape: White Solid-Crystals

Molecular weight: 118.16084

Ref: 54-BIMB1010

Guanidine Thiocyanate

CAS: 593-84-0

Formula: C₂H₅N₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 117.1529

Ref: IN-DA00IAJH

Guanidine thiocyanate

CAS: 593-84-0

Formula: CH₅N₃HSCN

Purity: ≥ 99.5%

Color and Shape: Colourless crystals or white crystalline powder

Molecular weight: 118.16

Ref: 7W-GE1694

Guanidine thiocyanate solution, 4M in water

CAS: 593-84-0

Formula: CH₅N₃HSCN

Color and Shape: Clear, colourless liquid

Molecular weight: 118.16

Ref: 7W-GE1849

Guanidine Thiocyanate

CAS: 593-84-0

M01833 - Guanidine Thiocyanate

Formula: C₂H₆N₄S

Purity: >99%

Color and Shape: Solid

Molecular weight: 118.16

Ref: 10-M01833

GUANIDINE THIOCYANATE 6M SOLUTION

CAS: 593-84-0

Formula: C₂H₆N₄S

Molecular weight: 118.16

Ref: 10-F549767

Guanidine thiocyanate

CAS: 593-84-0

Guanidine thiocyanate is used as a chaotropic reagent in cell lysis buffers as it disrupts cell and organelle membranes. Guanidine thiocyanate is especially suitable for purification of nucleic acids from crude cell lysates as it is a protein denaturant, allowing for separation of nucleic acids from the protein fraction. Guanidine thiocyanate also inactivates DNases and RNases, giving favourable yields of nucleic acids.

Formula: C₂H₆N₄S

Purity: Min. 98 Area-%

Molecular weight: 118.16 g/mol

Ref: 3D-G-8102

Guanidine Thiocyanate

CAS: 593-84-0

Applications Guanadine thiocyanate is a strong protein denaturant. It is used as a chaotropic agent for the isolation of intact RNA during the process of cell lysis. It shows strong irreversible inhibition on enveloped viruses. It is a key chemical used to isolate the virus’ genetic material, or RNA so that it can be tested.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Formula: CH₅N₃·CHNS

Color and Shape: Neat

Molecular weight: 118.16

Ref: TR-G838723

Guanidine thiocyanate

CAS: 593-84-0

Guanidine thiocyanate is used as a chaotropic reagent in cell lysis buffers as it disrupts cell and organelle membranes. Guanidine thiocyanate is especially suitable for purification of nucleic acids from crude cell lysates as it is a protein denaturant, allowing for separation of nucleic acids from the protein fraction. Guanidine thiocyanate also inactivates DNAses and RNAses, giving favourable yields of nucleic acids.

Formula: C₂H₆N₄S

Molecular weight: 118.16 g/mol

Ref: 3D-G-8100

Guanidine Thiocyanate (GTC) for molecular biology, 99%

CAS: 593-84-0

Formula: CH₅N₃·HSCN

Purity: min. 99%

Color and Shape: White, Crystalline compound, Clear, Colourless

Molecular weight: 118.16

Ref: SR-80272