DAPT

CAS: 208255-80-5

Ref. 02-J65864

Product Information

• Name: DAPT
• Synonyms: tert-butyl 2-{2-[2-(3,5-difluorophenyl)acetamido]propanamido}-2-phenylacetate, An-37124, DAPT (enzyme inhibitor), Dapt, Glycine, N-[(3,5-difluorophenyl)acetyl]-<span class="text-smallcaps">L</span>-alanyl-2-phenyl-, 1,1-dimethylethyl ester, (2S)-, Glycine, N-[2-(3,5-difluorophenyl)acetyl]-<span class="text-smallcaps">L</span>-alanyl-2-phenyl-, 1,1-dimethylethyl ester, (2S)-, Gsi-Ix, Ly-374973, N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester, N-[N-(3,5-Difluorophenacetyl)-<span class="text-smallcaps">L</span>-alanyl]-S-phenylglycine tert-butyl ester, N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-butyl ester, tert-butyl (2S)-({N-[(3,5-difluorophenyl)acetyl]-L-alanyl}amino)(phenyl)ethanoate, γ-Secretase inhibitor IX, Glycine, N-[(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-, 1,1-dimethylethyl ester, (2S)-, Glycine, N-[2-(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-, 1,1-dimethylethyl ester, (2S)-

Description

DAPT is used in the study of β-amyloid formation. DAPT has been shown to inhibit Notch signaling in studies of autoimmune and lymphoproliferative diseases, such as ALPS and lupus erythematosus, as well as in cancer cell growth, angiogenesis, and differentiation of human induced pluripotent stem cells. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 432.47
• Formula: C₂₃H₂₆F₂N₂O₄
• Color/Form: Solid, White
• InChI key: DWJXYEABWRJFSP-UHFFFAOYNA-N