1-Methylindole-3-carboxaldehyde, 98+%

CAS: 19012-03-4

Ref. 02-L02212

Product Information

• Name: 1-Methylindole-3-carboxaldehyde, 98+%
• Synonyms: 1-methylindole-3-carbaldehyde, 1-Methyl-1H-indole-3-carboxaldehyde, 1-Methyl-3-formylindole, 1-Methylindole-3-Carboxaldehyde, 1-Methylindole-3-carbaldehyde, 1H-Indole-3-carboxaldehyde, 1-methyl-, 3-Formyl-1-methylindole, Ai3-51477, Indole-3-carboxaldehyde, 1-methyl-, N-Methyl-3-formylindole, N-Methyl-3-indolecarboxaldehyde, N-Methylindole-3-carbaldehyde, NSC 83042

Description

1-Methylindole-3-carboxaldehyde is used as a reactant for preparation of nitroolefins and β-nitroalcohols via microwave- or ultrasound-assisted Henry reactions, reactant for synthesis of quinolinones via three-component Ugi reaction, reactant for synthesis of α-ketoamides as inhibitors of Dengue virus protease with antiviral activity in cell-culture, reactant for preparation of thiazolopyrimidinones as inhibitors of Bcl-2 proteins, reactant for preparation of vinylindoles via Peterson olefination or olefination with Nysted reagent, reactant for preparation of indolyl alkenes from microwave-enhanced Knoevenagel condensation as antibacterial agents 1-Methylindole-3-carboxaldehyde may be used in the synthesis of (Z)-3-(1-methyl-1H-indol-3-yl)-2-(thiophen-3-yl)acrylonitrile, via base-catalyzed condensation with thiophene-3-acetonitrile. It was also used in the preparation of monomer, required for the synthesis of poly(3-vinyl-1-methylindole). This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 159.19
• Formula: C₁₀H₉NO
• Purity: 98+%
• Color/Form: Crystals or powder or crystalline powder, White to cream to pale brown or yellow
• InChI: InChI=1S/C10H9NO/c1-11-6-8(7-12)9-4-2-3-5-10(9)11/h2-7H,1H3
• InChI key: KXYBYRKRRGSZCX-UHFFFAOYSA-N
• SMILES: Cn1cc(C=O)c2ccccc21