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Polyethylene glycol 12-hydroxystearate

Polyethylene glycol 12-hydroxystearate (Solutol HS-15) is a permeability enhancer.

<p>Polyethylene glycol 12-hydroxystearate is a non-ionic surfactant derived from the esterification of 12-hydroxystearic acid, typically sourced from castor oil, with polyethylene glycol. This compound exhibits amphiphilic properties, allowing it to reduce surface and interfacial tension between different phases. Its mode of action primarily involves facilitating the formation of stable emulsions by reducing the energy required to disperse one phase uniformly within another.</p>