APEX1 antibody
Ref. 3D-10-B9133M2
| 1mg | 244.00 € |
Product Information
Apurinic/apyrimidinic (AP) endonuclease is an enzyme that is involved in the DNA base excision repair pathway (BER). Its main role in the repair of damaged or mismatched nucleotides in DNA is to create a nick in the phosphodiester backbone of the AP site created when DNA glycosylase removes the damaged base. There are four types of AP endonucleases that have been classified according to their sites of incision. Class I and class II AP endonucleases incise DNA at the phosphate groups 3' and 5' to the baseless site leaving 3'-OH and 5'-phosphate termini. Class III and class IV AP endonucleases also cleave DNA at the phosphate groups 3' and 5'to the baseless site, but they generate a 3'-phosphate and a 5'-OH.
Chemical properties
Technical inquiry about: 3D-10-B9133M2 APEX1 antibody
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