MRGPRX4 antibody

Ref. 3D-70R-13164

Product Information

• Name: MRGPRX4 antibody
• Brand: Biosynth
• Description: The MRGPRX4 antibody specifically targets the Mas-related G protein-coupled receptor X4 (MRGPRX4), a GPCR encoded by the MRGPRX4 gene. This receptor is primarily expressed in human tissues, including sensory neurons and skin keratinocytes. Functionally, the activation of the receptor by specific ligands can trigger itch sensations, and it may also play a role in nociception. Researchers commonly use MRGPRX4 antibodies for techniques such as immunohistochemistry (IHC), Western blot (WB), and immunocytochemistry (ICC/IF) to study their expression and localization. Notably, these antibodies have undergone rigorous validation to ensure specificity. Furthermore, recent research highlights the role of MRGPRX4 in cholestatic itch, where bile acids act as natural ligands for this receptor. These findings provide a promising new drug target for anti-itch therapies.