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Amicoumacin B
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Amicoumacin B

CAS: 77674-99-8

Ref. 3D-AA177129

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Estimated delivery in United States, on Tuesday 17 Dec 2024

Product Information

Name:
Amicoumacin B
Synonyms:
  • (3S,4S,5S)-3-ammonio-4,5-dihydroxy-6-({(1S)-1-[(3S)-8-hydroxy-1-oxo-3,4-dihydro-1H-isochromen-3-yl]-3-methylbutyl}amino)-6-oxohexanoate (non-preferred name)
  • 3-Amino-2,3,6-trideoxy-6-[[(1S)-1-[(3S)-3,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl]-3-methylbutyl]amino]-6-oxo-<span class="text-smallcaps">D</span>-ribo-hexonic acid
  • <span class="text-smallcaps">D</span>-ribo-Hexar-6-amic acid, 3-amino-2,3-dideoxy-N-[1-(3,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl)-3-methylbutyl]-, [S-(R*,R*)]-
  • <span class="text-smallcaps">D</span>-ribo-Hexonic acid, 3-amino-2,3,6-trideoxy-6-[[(1S)-1-[(3S)-3,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl]-3-methylbutyl]amino]-6-oxo-
  • Ai 77B
Description:

Amicoumacin B is a complex antibiotic that has high cytotoxicity against subtilis and other species of bacteria. It is an asymmetric synthesis of two molecules, amicoumacin A and amicoumacin B, which are both produced by the bacterium Streptomyces sp. Amicoumacin B has been shown to be a potent inhibitor of cervical cancer cells in vitro. This antibiotic is composed of a hydroxyl group and an ester linkage between the hydroxycarboxylic acid moiety and the amino moiety. It has been shown to have a high blood level in humans, with a type strain from human plasma showing an enantiomer ratio of 97:3 in favor of the levo-amino acid. The genus Streptomyces includes many species including S. griseus, S. lividans, S. viridochromogenes, and S. violaceoruber.
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Notice:
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Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Purity:
Min. 95%
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
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Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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